Doing nothing at all is cheaper, faster and.. well, not more effective, but it's not particularly all that much -less- effective.
Here's the rub.. if your content is popular - and I'm guessing it is - then it will end up on YouTube. So what do you do..
A. Pay a staffer to monitor YouTube continually and a legal department (or lawyer) to draft legal complaints (DMCA takedown notice if applicable), send this to Google, wait for reply and video takedown, then wait some more to see if the person who uploaded is feeling fresh and decides to tell Google that they think the upload was fair use or somesuch, and you get to write some more legal documents, or they just bow their heads and admit that it was infringement at no cost to them beyond reading the youtube e-mail subject (don't even bother with the body content). In the mean time, start your work with the legal peeps to deal with the other 2 videos of the exact same show, uploaded while you were dealing with the aforementioned. After all.. Google isn't obligated to remove -all- the videos.. just the one you complained about.. and you can only complain about one.
B. Try to sue Google to get them to implement better filtering methods, fingerprinting, removal of -all- the videos that match ones you've already complained about, etc. and spend a whack of cash... that you would've been spending under A anyway.. but of course go nowhere because the courts do firmly side with Google on this.
C. do nothing.
of course there's also...
D. upload the videos yourself, be the official channel for that show, and people will have less of a reason to visit JoePirate's version of the video with crappy compression and "A JOOOOOEEEEEEEEE PIIIRAAAAAATE production!!!!" leader in front of it with its feeble "I'm not the copyright holder - I do not mean to infringe on any copyright!" description that would make me wonder about the uploader's frame of mind if not for the fact that this is, after all, YouTube.
To some, though, option B may seem more attractive.. perhaps it'll fly in some jurisdiction eventually.. but option A is certainly completely pointless. Option C is the only worthwhile approach if you abhor option D for some reason.