The toxicity is actually an indirect effect. The fluorescent dyes can in their excited states react with molecular oxygen to produce reactive oxygen species that damage tissues. By reducing the time and energy of excitation of the fluorophores (by only exciting those actually about to be scanned by the microscope), this technique reduces the amount of toxic byproducts.
The one that drives me crazy is removing the ethernet port on MacBooks. Which wouldn't be too bad if Apple's USB or Thunderbird ethernet adapters lasted more than 6 months before breaking, but I'm on my 5th in slightly over 2 years now... finally bought a third party one in the hopes that it will be less frail.
Most artificial sweeteners sold in powder form contain a simple sugar or starch to add bulk and give the product free-flowing granules more similar to sugar. Since saccharin, sucralose, and aspartame all taste hundreds of times sweeter than sugar, they are used in much lower amounts, with bulk added for the consumer-serving preparations so that you don't have to add micrograms of sweetener to your coffee to get the equivalent sweetness of sugar. Either glucose (usually listed as dextrose) or maltodextrin are generally used, which is interesting since it means that sugar substitutes generally contain a small amount of carbohydrates. The little single-serving packets tend to have about 3 (kilo)calories each; in the US, the FDA allows foods with less than 5 calories to be labeled as "zero calorie," so they generally are.
I note that this study did happen to use all powder-form sweeteners (dissolved in water) which means that there would some small amount carbohydrate in the solution. That's a perfectly reasonable way to run this study, since these are widely used preparations of these sweeteners, but I do wonder if there might be a difference with a genuinely digestible-carbohydrate-free preparation.
The issue isn't that there isn't a text book or a clear laymen description of the problem it comes when someone says: so prove to me that the churn of the lower atmosphere can carry these gasses to the upper atmosphere and the scientist starts talking about climate models which cannot predict any specific event with a high degree of accuracy but do tend to predict trends with great accuracy. To me this is like saying: what is the energy of a particle in a chamber at a defined pressure, temperature and density. The answer is very easy to give the average but essentially impossible to give the exact unless your model knows ALL of the inputs (i.e. every momentum vector and quantum state of every atom contain within the chamber).
Doubt isn't the opposite of faith; it is an element of faith. - Paul Tillich, German theologian and historian