When it was announced in 2008, this was a big deal for retro gamers. I just can't believe that they are still marketing it in 2014 though. This is a product that comes from another era, and was never improved. I have an old Sega Nomad that looks more modern.
Today you can choose from a number of high-quality snap-on bluetooth controllers for your smartphone and get so much more than what OpenPandora offers. There are incredible Android emulators for every system, including uncommon platforms like the Sega Saturn. Going this route, you can spend as much as you like on a controller, and utilize that super-computer (relative to OpenPandora at least) in your pocket with a beautiful, large display. And you don't have to deal with the bulk of a giant first-gen Nintendo DS clamshell.
With a bluetooth controller, you can even connect your device to a TV via HDMI and play wirelessly in HD, adding scanlines and filters to get a beautiful gaming experience. OpenPandora will never be able to do that.