I'm American, but the first stick shift I learned to drive was British. Oddly, the only controls I had difficulty adjusting to were the turn signals and windshield wipers. I could never remember if they were mirrored or not.
I'm left-handed and British, I drive a manual car and change gear with my left hand. If I've got only one hand on the wheel it's usually my right but I'm cool with both. I've driven the occasional left-hand drive car and after half an hour or so I'm used to reaching on my right for the gear stick, likewise on tractors with the stick in the middle. I don't think it makes a lot of difference.
What I find hardest to get used to is the position of the indicators (turn signals) when I change between cars. The majority (but far from all) of cars on the road in the UK seem to have them on the left and the wipers on the right, I drive an older british-made car with indicators on the right and wipers on the dash and I get that one wrong more often than anything else. The other one is strangely enough the throttle travel, after driving a friends car for a while I get in mine and think it's gutless and underpowered, right until I realise/remember there's a full two inches more travel on the pedal :-)