Best Patient Relationship Management (PRM) Software for NextGen Healthcare EHR

Luma Health was founded on the idea that healthcare should work better for all patients. Luma’s Patient Success Platform™ is designed to go beyond disjointed patient engagement initiatives to connect patients to their providers across the entire healthcare journey – access and operational, clinical, and financial. This orchestration is supported by Luma Bedrock™ data-driven best practices, based on more than 700 million data points across more than 80 million patient interactions. Luma serves more than 600 health systems, integrated delivery networks, federally qualified health centers, specialty networks, and clinics across the United States, and today orchestrates the care journeys of more than 50 million patients.

Klara offers a comprehensive platform that integrates secure messaging, remote monitoring, and video consultations, all designed to enhance patient communication. This robust system consolidates various patient workflows into a single interface, enabling the automation of essential patient interactions and optimizing processes for all types of appointments, thereby ensuring a top-tier patient experience. With the capability to connect with patients remotely through secure messaging and video visits, Klara provides a cohesive and user-friendly experience without requiring patients to log in, check their email, or download an app. Patients, whether new or returning, can easily communicate with staff directly from the website, facilitating increased appointment bookings and enabling continuous patient engagement around the clock. Additionally, forms can be digitized, allowing patients to complete them conveniently on their own devices, with text notifications ensuring that they receive and sign forms promptly. Furthermore, messages are systematically directed to shared inboxes, allowing multiple team members to address inquiries or manage tasks pertinent to their specific roles efficiently, which ultimately enhances team collaboration and improves overall patient care.

Artera Harmony is a secure agentic platform that deploys AI agents for voice and text across healthcare communication workflows — scheduling, intake, referrals, billing, care gaps, and more. The platform integrates with leading EHRs via real-time API connections, with automated writebacks and 50+ healthtech vendor integrations through the Artera Marketplace. Multi-channel messaging (SMS, voice, web) supports 109+ languages. Paired with AI Service Squads — dedicated teams of AI builders who work directly with provider organizations — Artera addresses urgent workflows from day one and custom-builds solutions as operational needs evolve. 2B+ annual communications. #1 Best in KLAS for Patient Communications (2026). FedRAMP Class D Certification. 11+ years healthcare-native. 1,000+ provider customers.