Best Operational Technology (OT) Security Software for Microsoft 365

Find and compare the best Operational Technology (OT) Security software for Microsoft 365 in 2026

Use the comparison tool below to compare the top Operational Technology (OT) Security software for Microsoft 365 on the market. You can filter results by user reviews, pricing, features, platform, region, support options, integrations, and more.

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    Microsoft Defender for IoT Reviews

    Microsoft Defender for IoT

    Microsoft

    $0.001 per device per month
    Continuous asset discovery, vulnerability management, threat detection, and continuous asset discovery for your Internet of Things and operational technology devices (OT). Ensure IoT/OT innovation by accelerating IoT/OT innovation through comprehensive security across all IoT/OT devices. Microsoft Defender for IoT is an agentless, network-layer security solution that can be quickly deployed by end-user organizations. It works with diverse industrial equipment and integrates with Microsoft Sentinel and other SOC tools. You can deploy on-premises and in Azure-connected environments. Microsoft Defender for IoT is a lightweight agent that embeds device-layer security in new IoT/OT initiatives. Passive, agentless network monitoring allows you to get a complete inventory and analysis of all your IoT/OT assets. This is done without any impact on the IoT/OT networks. Analyze a variety of industrial protocols to identify the device details, including manufacturer, type, firmware level, IP or Media Access Control address.
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    Armis Centrix Reviews
    Armis Centrix™ unifies cybersecurity operations by delivering continuous discovery, monitoring, and protection of every asset across complex hybrid networks. Its AI-powered intelligence engine enables security teams to detect unmanaged devices, assess vulnerabilities, and mitigate risks before attackers can exploit them. Organizations can manage IT systems, industrial OT environments, medical IoMT fleets, and IoT devices from a single platform with zero blind spots. The platform supports both on-premises and SaaS deployments, making it flexible for industries like healthcare, utilities, manufacturing, and critical infrastructure. VIPR Pro enhances the platform with automated remediation workflows, helping teams prioritize issues based on real-world threat activity. Early Warning intelligence provides insight into vulnerabilities actively being weaponized, ensuring organizations can act ahead of threats. Armis Centrix™ also improves business outcomes by increasing operational efficiency, supporting compliance, and strengthening resilience. Trusted by global enterprises and recognized by Gartner and GigaOm, Armis Centrix™ is built to meet the cybersecurity demands of modern digital environments.
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    Darktrace Reviews
    Darktrace Behavioral Defense Platform is an AI-powered cybersecurity platform designed to secure modern enterprises in the AI era. The platform provides unified visibility, continuous behavioral monitoring, and autonomous response across AI, people, and infrastructure. Darktrace uses Adaptive AI to continuously learn how an organization normally behaves across users, systems, relationships, AI interactions, and operational patterns. This behavioral understanding helps security teams identify anomalies, detect novel threats, and respond with speed and precision. The Secure AI capabilities help organizations monitor AI adoption, prompts, agents, development activity, and Shadow AI. The Secure People capabilities protect email and collaboration environments from phishing, account compromise, and other human-centered risks. The Secure Infrastructure capabilities help detect, investigate, and contain threats across network, cloud, identity, endpoint, and operational technology environments. Real-Time AI Analyst supports AI-driven detection, investigation, triage, response, prioritization, and reporting for security teams. By combining behavioral profiling, cross-domain visibility, autonomous response, AI security, email protection, infrastructure defense, and SOC support, Darktrace helps enterprises improve security outcomes in real time.
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    Darktrace / OT Reviews
    Darktrace / OT is an advanced AI-driven security platform specifically designed for safeguarding critical infrastructure, integrating threat detection and response with contextualized risk management for operational technology that surpasses mere CVE scoring. This innovative solution identifies and visualizes devices operating on both IT and OT protocols, offering comprehensive visibility throughout all levels of the Purdue Model from a secure foundation. By employing both passive and active scanning techniques, it maintains an up-to-date inventory of assets while highlighting vulnerabilities and the status of devices nearing their end of life. Furthermore, its real-time monitoring capabilities extend to specialized industrial protocols, production assets, and connected IT systems, ensuring thorough oversight. The Self-Learning AI component adeptly recognizes standard operational patterns, thereby enabling the detection of insider threats as well as known, unknown, and zero-day vulnerabilities on a large scale. In addition, the Cyber AI Analyst feature performs automatic investigations of activities across both IT and OT environments, efficiently prioritizing critical incidents and summarizing findings for production engineers and security analysts alike. Lastly, the Autonomous Response functionality allows for the initiation of specific, pre-approved measures to effectively halt and contain emerging threats, thereby enhancing the overall security posture of the infrastructure. This holistic approach makes Darktrace / OT an indispensable tool in the realm of cybersecurity for critical systems.
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