Best Multimodal Models for Databricks

Claude Mythos 5.1 represents Anthropic's latest advancement in the Mythos-class of models, tailored for sophisticated applications in cybersecurity, biology, scientific investigation, programming, and extensive knowledge-oriented tasks. While it shares the same foundational architecture as Claude Fable 5.1, it is differentiated by unique safety measures: Fable 5.1 is widely accessible, whereas Mythos 5.1 is limited to select trusted access programs designed with specific safeguards for cybersecurity and life sciences research. This model establishes a new benchmark in performance for autonomous coding and showcases unparalleled cyber capabilities among all Anthropic models released thus far. In the realm of scientific research, Mythos 5.1 can effectively handle specialized tools and intricate workflows related to molecular design, computational biology, and various technical fields. During testing by Anthropic, it successfully engineered high-affinity protein binders for multiple targets, achieving its highest recorded hit rate to date. Additionally, it demonstrated proficiency in optimizing seven different open-source deep learning models focused on protein and genomics. By pushing the boundaries of what is possible, Mythos 5.1 is positioned to make significant contributions to future research and development endeavors.

GPT-6 Astra is an advanced general-purpose AI model from OpenAI designed for demanding agentic, technical, scientific, and professional workflows. The model combines reasoning with computer-use capabilities that let it interact with applications, websites, development environments, productivity software, and specialized tools. It can perform activities such as online research, CRM updates, form completion, calendar organization, data analysis, software testing, troubleshooting, and frontend quality assurance. Astra is also trained for professional artifact creation, including documents, presentations, spreadsheets, analyses, websites, applications, and visual designs that follow provided templates and business conventions. Its software engineering capabilities support complex coding, codebase understanding, debugging, database migration, verification, and extended autonomous development tasks. OpenAI has also introduced a Codex context system for Astra that can maintain notes across context windows and search earlier conversation and tool history instead of relying exclusively on repeated summarization. Scientific capabilities span areas such as mathematics, biology, chemistry, health, data analysis, and the use of specialized research software. The model includes strengthened alignment and cybersecurity safeguards intended to help it remain within authorized task boundaries while supporting legitimate activities such as secure code review and vulnerability remediation. GPT-6 Astra is available across supported ChatGPT plans and developer platforms, including the OpenAI API and Amazon Web Services infrastructure.

Claude Fable 5.1 is a frontier AI model from Anthropic built for demanding coding, research, knowledge work, and autonomous multi-step workflows. It delivers higher performance than Claude Fable 5 across benchmarks covering scientific research, terminal-based coding, business automation, computer use, multidisciplinary reasoning, and agentic software development. The model is particularly suited to long-running tasks where it must investigate problems, use tools, maintain context, verify intermediate work, and continue operating with limited supervision. Early evaluations highlighted improvements in areas such as root-cause analysis, code review, browser automation, financial research, document drafting, slide creation, and complex engineering workflows. Fable 5.1 also introduces lower cache-read pricing, which Anthropic says can reduce costs by roughly 25% for typical workloads and considerably more for context-heavy agentic tasks. Enterprise customers can use new privacy-oriented safeguard options that are designed to support zero-data-retention-style deployments while still maintaining misuse protections. Cybersecurity safeguards have also been refined to intervene less often on legitimate defensive work while continuing to restrict higher-risk activities such as exploit generation. Anthropic offers the model through Claude Code, Claude Cowork, Claude.ai, the Claude API, and supported cloud platforms. Claude Fable 5.1 is intended for developers, researchers, enterprises, and professional teams that need strong reasoning and coding performance without relying on Anthropic’s most restricted-access model tier.

Claude Opus 5 is Anthropic’s new state-of-the-art Opus model for coding, knowledge work, automation, science, and everyday AI assistance. The model is designed to provide near-frontier intelligence at a lower cost than Claude Fable 5 while keeping the same base pricing as Opus 4.8. Claude Opus 5 performs strongly on software engineering benchmarks, business task automation, computer use, novel problem solving, visual generation, and scientific research tasks. Users can adjust effort settings to trade off intelligence, speed, and token usage depending on the task. The model is also better at verifying its work, iterating carefully, building test harnesses, debugging root causes, and solving multi-step engineering problems. Anthropic highlights improvements in life sciences, including structural biology, organic chemistry, bioinformatics, and protein-related tasks. Claude Opus 5 includes alignment and safety safeguards designed to support beneficial work while blocking higher-risk cybersecurity and biology misuse. It is available through Claude.ai, Claude Max, Claude Pro, Claude Code, Claude Cowork, and the Claude API under the model name claude-opus-5. By combining stronger reasoning, coding ability, scientific capability, configurable effort, Fast mode, and enterprise-ready deployment options, Claude Opus 5 gives users a powerful model for demanding daily work.

Claude Fable 5 is Anthropic’s most capable generally available AI model, built to tackle demanding tasks across software development, research, business analysis, scientific exploration, and enterprise productivity. The model demonstrates state-of-the-art performance in coding, reasoning, visual understanding, long-context processing, and autonomous task execution. Claude Fable 5 can analyze large codebases, interpret complex documents and datasets, generate detailed reports, and assist with advanced decision-making processes. Its enhanced memory capabilities allow it to remain effective during long-running workflows and multi-step projects. The model also delivers strong performance in image analysis, chart interpretation, scientific reasoning, and technical problem-solving. Anthropic has incorporated advanced safety classifiers that detect certain high-risk topics and automatically redirect those interactions to a more restricted model experience. These safeguards are designed to reduce misuse while still providing productive assistance for legitimate users. Claude Fable 5 is available through the Claude platform and API, enabling developers and organizations to integrate advanced AI capabilities into their applications and workflows. The platform is designed to help businesses improve productivity, accelerate innovation, and streamline complex knowledge work.

GPT-5.5 is a next-generation AI system built for execution-heavy workflows across coding, research, business analysis, and scientific tasks. It can interpret complex instructions, break them into actionable steps, and carry them through to completion while interacting with tools and systems. The model supports creating applications, generating reports, analyzing datasets, and navigating software environments seamlessly. It also integrates with workspace agents—custom AI agents that automate recurring and multi-step processes across teams. These agents can handle tasks such as lead research, reporting, and workflow automation, either on demand or on schedules. GPT-5.5 enhances productivity by reducing manual effort and enabling continuous task execution across tools. With enterprise-grade safeguards and monitoring, it ensures secure and controlled automation. It is well-suited for organizations looking to scale operations and improve efficiency through AI-driven workflows.

GPT-5.5 Pro is a next-generation AI model built for execution-heavy tasks across coding, research, business analysis, and scientific workflows. It can interpret complex instructions, break them into steps, and carry work through to completion using tools and automation. The model supports tasks such as generating documents, building applications, analyzing datasets, and navigating software environments. It is designed to operate across tools, enabling seamless workflows from idea to output. In addition, GPT-5.5 Pro integrates with workspace agents—customizable AI agents that automate recurring and multi-step processes across teams. These agents can handle tasks like lead research, reporting, and workflow automation, running independently or on schedules. Built with enterprise-grade safeguards, the model ensures secure and controlled automation. It helps organizations improve productivity by reducing manual effort and accelerating decision-making. GPT-5.5 Pro is ideal for teams looking to scale operations and handle complex workloads efficiently.