Best Manufacturing Software for Microsoft Dynamics 365

Qualio is a purpose-built quality and compliance platform for life sciences companies operating in complex, high-stakes regulatory environments. Medical device, SaMD, biotech, and pharma teams use Qualio to replace fragmented eQMS tools, spreadsheets, and consultant-driven audits with a single, validated system that delivers continuous audit and inspection readiness. Qualio combines a modern eQMS with Compliance Intelligence—an AI-driven layer that continuously evaluates how well real operating data aligns with regulatory requirements. Instead of treating audits as one-off events, teams gain always-on visibility into compliance coverage, risk exposure, and readiness across FDA, ISO, EU MDR, GxP, and software-intensive standards. Core quality workflows—document control, training, CAPA, change management, supplier quality, and design controls—are directly connected to regulatory obligations and objective evidence. Deep integrations with Jira, Azure DevOps, GitHub, TestRail, and Salesforce automatically capture proof from development and operational systems, eliminating manual evidence gathering and reducing compliance drag on engineering teams. Compliance Intelligence runs multi-standard gap analysis in under an hour, flags emerging risks before they become findings or 483s, and maps reusable evidence across frameworks to accelerate submissions and market expansion. All insights are explainable and traceable back to specific clauses and internal policies, supporting validation and audit expectations. The result: audit readiness in weeks instead of months, fewer fire drills, faster launches, and lower long-term compliance cost. Qualio turns compliance from a reactive burden into a predictable, scalable system.

Tractian is the Industrial Copilot for maintenance and reliability, combining hardware and software solutions to monitor asset performance, manage industrial operations, and implement predictive maintenance strategies. Its AI-driven platform empowers businesses to prevent unplanned equipment downtime and boost production output. The company is headquartered in Atlanta, GA, and extends its presence globally with offices in Mexico City and Sao Paulo. Learn more at tractian.com.

The Asset Guardian (TAG) Mobi: Tackle Downtime with TAG Mobi TAG Mobi is a fully embedded preventive maintenance and asset management (EAM) solution within Microsoft Dynamics 365 Business Central. Designed for modern manufacturing and infrastructure operations, TAG Mobi helps reduce risk, minimize downtime, and streamline maintenance workflows—all from within your existing Business Central environment. From proactive asset health monitoring and predictive maintenance to real-time mobility and AI-powered adoption tools, TAG Mobi equips maintenance teams with everything they need to boost performance and take control of asset operations. Key Features: • Fully embedded in Microsoft Dynamics 365 Business Central • Real-time mobile access for on-the-go asset tracking • Predictive maintenance to reduce unplanned downtime • AI-assisted onboarding for faster adoption • Advanced APM tools to monitor asset health and anticipate failures No silos. No extra software. Just a seamless, native experience that empowers maintenance teams and provides managers with the insights they need—right inside Business Central.

Project Insight is a strategic project and portfolio management software that gives companies a complete picture of the work happening across their entire organization. Streamline workflows, automate processes, enhance collaboration, and capture project data points from all your teams and systems in one central command center so you can make confident decisions about business. Manage work at the project, program or portfolio levels and integrate with the tools you already use, including Azure DevOps, Jira, Microsoft, Salesforce, and ServiceNow, and HubSpot to eliminate the need to manually key in data across teams. With the most views of any project management platform, teams can keep tabs on assignments, status, risks, resources, capacity, schedules, budgets, and more. Project Insight also offers free view only seats for clients. The power of AI can be used to assign action items after meetings, predict future capacity, balance workloads, & select the right resources. Additional AI-powered features include what if simulations to generate tradeoffs when priorities change and AI-generated project templates (WBS). Whether you are moving from basic spreadsheet project tracking or you have a sophisticated PMO with a complex web of unique business processes, Project Insight has the broad feature set to help you grow as you go. Our onboarding teams are known for being the best in the business and our platform can be fully customized to manage projects and data the way your company needs to.

Visual Planning is a powerful scheduling and resource management tool that's simple to use. Visual Planning is used by thousands of organizations to share their schedules and work more efficiently together.

Digit is a software that helps companies track their operations in real-time. The cloud-based software includes features for purchasing and receiving, inventory management as well as production, sales and fulfillment. Digit's goal is to integrate siloed system via a single operating system in order to help organizations plan and execute, measure, optimize and connect. The software offers capabilities such as creating purchase orders, serialized inventories, quality control, billing of materials and routings, sales order management and guided picking and packaging, as well integrations with QuickBooks.

TLM QMS Software is a powerful and robust quality, risk and material management software (QMS) which is validated and 21 CFR Part 11 compliant. TLM is a cutting-edge, all-in-one quality management system that can be customized to integrate with online CRM software, QuickBooks or ERP databases. Total Lean Management (TLM) QMS Software is specifically intended to be a low cost, highly integrated, flexible and continuously improving landscape to which specialty systems can be added where needed to create the digital business landscape that enables work flows the way your company needs them to work.

Stop problems as they happen with real time visibility from the factory floor. Mingo Smart Factory is the easiest to use, fastest to implement manufacturing analytics system that you can’t outgrow. This productivity platform is a plug-and-play solution that seamlessly works on top of your current hardware. Mingo is a manufacturing productivity and analytics tool that gives real-time visibility to the factory floor. It helps to reduce downtime, improve on time delivery and increase profitability for manufacturing companies. Mingo empowers manufacturers with analytics and manufacturing productivity software to start small, think big and move fast. It's not just software - Mingo includes sensors that will bring older machines into the 21st century. Mingo is the digital toolkit you need to reduce downtime, real time visibility, replace Excel, unlock capacity and improve OEE. Use Mingo to reduce waste and improve efficiency, as well as drive your next phase in business growth. All this from one platform. It's so efficient you'll be amazed how you managed your factory without it.

GainSeeker Suite, the enterprise-level SPC software and manufacturing Intelligence platform, compiles disparate manufacturing operations data and turns it into useful, actionable intelligence. Our clients can triage, prioritize, address, and resolve issues faster and more consistently. They can quickly identify the root cause of problems and uncover hidden opportunities to increase revenue, grow margins and improve asset performance with automated drill down analytics. GainSeeker connects data from many systems. It can connect to vision systems, PLC's, and gages. You can also connect to ERP and MES systems to connect all of your manufacturing data.

Sage Supply Chain Intelligence brings clarity and control to complex supply chains by unifying teams, systems, and suppliers in one platform. From PO creation to warehouse delivery, every milestone is tracked and updated in real time. Automated workflows and centralized communication replace spreadsheets and siloed emails, giving your team more time to focus on growth—not chasing down status updates. With Sage Supply Chain Intelligence, you get instant access to supply chain insights, improved supplier performance, and faster decision-making—so you can move with confidence and deliver on time.

It can be used in conjunction with your ERP / MRP, but not as a replacement! Waterloo Manufacturing Software developed TACTIC, a highly customizable, advanced planning and manufacturing scheduling software. TACTIC is suitable for both batch and discrete industry manufacturers. It reduces inventory and supply costs and improves customer service. TACTIC is used by manufacturers to guarantee delivery, plan and schedule production, plan materials and capacity, and deal effectively with problems and changes. TACTIC's advanced scheduling algorithms and what-if options allow management teams to balance what's best for the business with what's best for customers. TACTIC's technical advisors at Waterloo Manufacturing Software offer a variety of pre-sale as well as post-sale services. These services allow you to both assess the technology and gain ever-increasing benefits from its use in your business.

UpKeep is a mobile-first software for facilities and equipment maintenance that is trusted by some the largest companies in the world. UpKeep allows asset and facility management teams to get better data and collaborate seamlessly to improve productivity. It includes tools to create work orders on the go, keep track of all current or upcoming work orders and monitor the health of locations.

At DynamicsPrint®, we understand the intricate dynamics of the printing and packaging industry and recognize the need for a comprehensive solution to propel businesses forward. Our ERP software system is meticulously crafted to empower your print-centric enterprise with efficiency, agility, and innovation. A common theme in the feedback we receive from our partners is a boost in efficiency and productivity, with employees being able to reduce the time and effort spent completing common tasks of up to 50%. Organizations also report higher quality work, helped by insights and guidance, from suggested actions to faster access to valuable business data. We design and customize DynamicsPrint® to ensure the system meets the highest standards of efficiency and stability. We are also renowned for our strong dedication to implementation and optimization. With 30 years of experience, we deliver an ongoing partnership that extends well beyond the launch of a software program. Leverage the latest in technology from cloud-based solutions, AI-driven insights, and IoT integration, positioning your printing or packaging business at the forefront of technological advancement.

MangoGem created the MangoGem APS Optimizer to optimize planning and scheduling. This tool was designed to go beyond current APS systems and make it accessible and easy for organizations of all sizes. It employs a unique combination mathematical optimization methods, heuristics, and other advanced information technology like artificial intelligence. MangoGem's APS Optimizer can help you improve performance, increase efficiency, and reduce costs. Scheduling optimization that goes beyond the state-of-the art APS systems. A powerful Advanced Planning and Scheduling System that includes a flexible scheduling optimizer.

VKS makes it simple for companies to get rid of paper work instructions and transform into a digital factory. There are many benefits to our visual work instruction solution, including: No need for paper! Digital work instructions can be created with better results. You can reduce your defects up to 95% by performing in-process quality checks. Standardize best practices to increase productivity by 20% You can track your processes 100% with 100% certainty and real-time control. You can accelerate and improve the accuracy of your operational decision making. Capture tribal knowledge to close the skills gap.

Cleo Integration Cloud is an award-winning EDI solution that enables B2B integration and visibility. CIC simplifies EDI problem resolution, accelerates partner onboarding and automates EDI automation. End-to-end integration transparency across EDI and non-EDI integrations, as well as API integrations, enables you to grow revenue-generating processes faster and better. CIC optimizes thousands of supply chain for logistics providers, manufacturers and wholesalers. Our cloud-based B2B platform, which includes seamless ERP integration, TMS and WMS integrations, transforms complex, costly processes into efficient, agile and scalable operations. Our ecosystem integration approach provides the best B2B capabilities, so you can automate EDI transactions and API transactions, quickly onboard partners, gain competitive control, and more.

Smart Software, a leading provider in demand planning, inventory optimization, and supply chain analytics solutions, is based in Belmont, Massachusetts USA. Smart Software was founded in 1981 and has helped thousands of customers plan for future demands using industry-leading statistical analysis. Smart Inventory Planning & Optimization is the company's next generation suite of native web apps. It helps inventory-carrying organizations reduce inventory, improve service levels, and streamline Sales, Inventory, Operations Planning. Smart IP&O is a Digital Supply Chain Platform that hosts three applications: dashboard reporting, inventory optimization, demand planning. Smart IP&O acts as an extension to our customers' ERP systems. It receives daily transaction data, returns forecasts and stock policy values to drive replenishment planning and production planning.

Founded in 2004, edinn has become one of the most popular Industry 4.0 Platforms in the world. It is used by thousands around the globe. Edinn is the foundation platform for any Industry 4.0 project. It includes all the essential elements and, on these, uses the favorite development environment. It allows you to solve any need through its standard API. It is the reason why edinn partners are so successful in their Industry 4.0 projects. Edinn creates the platform, but it needs partners in order to implement it in customers. With edinn, partners have a complete back-end that allows them to manage and develop an Industry 4.0 business line. This Partner + edinn model offers greater service and commitment for the final user. The platform includes 13 modules as well as many downloadable add-ons.

Azumuta is an all-in-one system to digitalize your shop floor operations. Become a paperless factory, save time in manual data entry, and prevent errors by creating and managing digital work instructions, audits, employee training, and quality management reports from a single platform.

MachineMetrics Industrial IoT Platform transforms your shop floor data from insights into actions with powerful apps that reduce machine downtime, increase your throughput, and maximize profitability driven by your manufacturing equipment.

Enhance resilience by implementing an agile supply chain that can swiftly adapt to innovation demands and address quality concerns, while also accommodating shifting customer requirements and outdated components to maintain compliance and minimize delays. Utilize artificial intelligence to anticipate demand and ensure timely product delivery through real-time supply and production planning, effectively placing resources where they are needed most. Leverage predictive analytics to refine and automate key aspects of inventory management, warehousing, fulfillment, material sourcing, and logistics to boost delivery performance. Establish flexible manufacturing systems and processes by integrating predictive technologies, the Internet of Things (IoT), and mixed reality, which can lead to increased throughput, improved quality, and timely deliveries while also cutting costs. By implementing proactive maintenance strategies, companies can reduce equipment downtime and enhance overall equipment effectiveness (OEE), thereby extending the lifespan of machinery. In this way, businesses are optimizing their operations through advanced Supply Chain Management techniques. Ultimately, the focus on developing agile manufacturing and distribution systems is key to thriving in today’s dynamic market landscape.

LeanDNA, a SaaS platform for global manufacturers, helps reduce excess inventory, prevent shortages and establish operational command. The platform is factory-centric and bridges the gap between complex supply chains, inventory operations, and their labor-intensive methods of reporting, analytics, inventory decision making, and their outdated, labor-intensive methods. The software can be integrated with any ERP system. It normalizes data across disparate ERP systems, planning tools, as well as other supply chain execution tools. The platform uses artificial intelligence to provide prescriptive and prioritized insights to procurement teams to optimize inventory, improve supply chain efficiency, decrease working capital, and unlock new business opportunities.

For over three decades, VistaTrac™ has been a trusted solution within the meat industry, with over half of our clientele consisting of meat-related businesses. Companies engaged in wholesale, foodservice, distribution, online retail, slaughter, and custom processing have all experienced significant advantages from utilizing VistaTrac. This system allows users to weigh and tally loads while recording essential vendor information. It provides a platform to compare live weights against hot weights and access receiving reports that detail shrinkage. Additionally, users can print carcass tags for inventory management, thus streamlining operations and eliminating the need for kill-floor paperwork by incorporating a digital BSE Checklist alongside tailored data collection methods. The system enables the documentation of retained and condemned carcasses as well. Customized slaughter orders can be generated, complete with specific cut instructions for processing client animals. Furthermore, the ability to print customer logos and UPCs enhances product value. Foodservice operations benefit from just-in-time order processing, while cut slips with assigned tables and truck route numbers facilitate order management by route, allowing offices to monitor the status of route fulfillment. Additionally, verifying routes is made efficient by scanning all products during staging and generating pallet labels for easy identification. Overall, VistaTrac offers a comprehensive suite of tools designed to optimize meat processing and distribution, ensuring a smoother workflow and improved accuracy.

Aptean is a world-leading provider of industry-specific software. This software helps distributors and manufacturers run their businesses efficiently and grows their profits. Aptean's products and services, as well as unmatched expertise, allow businesses of all sizes and industries to be ready for what's next, now®. Aptean has offices across North America, Europe, and Asia-Pacific. Its headquarters are in Alpharetta in Georgia. Aptean Food & Beverage ERP provides an end-to-end solution for food and beverage processors, manufacturers, distributors, and distributors.

Aegis Software's FactoryLogix is revolutionizing the field of Manufacturing Execution Software (MES). This innovative platform provides cutting-edge technology through a comprehensive suite of software modules designed to enhance manufacturing processes. Serving as an all-encompassing solution, FactoryLogix encompasses the complete manufacturing lifecycle, starting from product introduction and material logistics to manufacturing execution and robust analytics with dashboards. By offering such extensive capabilities, FactoryLogix equips manufacturers with the agility, insight, and oversight essential for maintaining a competitive edge in today's fast-paced market. This holistic approach ensures that businesses can optimize their operations at every stage.