Best Large Language Models for NVIDIA NIM

NVIDIA Nemotron 3.5 Super VL is a multimodal foundation model developed for AI agents that require reasoning, visual understanding, coding, and multistep task execution. Its 120-billion-parameter mixture-of-experts architecture activates approximately 12 billion parameters per token, enabling efficient inference while maintaining substantial model capacity. The model processes text, images, documents, and video within a unified system that combines multimodal interpretation with instruction following and tool use. Its document intelligence capabilities include extracting information from tables, analyzing charts, interpreting page layouts, and processing multipage documents. Video understanding features support visual information retrieval, content review, incident analysis, and reasoning across recorded sequences. The model also supports software engineering tasks such as code analysis, error identification, debugging, testing, and recommending fixes. Developers can customize Nemotron 3.5 Super VL using NVIDIA NeMo for supervised fine-tuning, low-rank adaptation, and reinforcement learning with domain-specific data. Its inference optimizations include speculative decoding, context reuse, multi-token prediction, and NVFP4 quantization to improve throughput and reduce computational requirements. The model is available with open weights and supports deployment across compatible local hardware, enterprise data centers, and cloud infrastructure.

NVIDIA Nemotron 3.5 Bolt is a series of efficient AI models developed by NVIDIA for running autonomous agents and conversational applications directly on local hardware. The family consists of Bolt 74B-A9B 24GB and Bolt E4B 4GB, which address different performance and memory requirements. Bolt 74B-A9B uses a mixture-of-experts architecture with 74 billion total parameters and approximately 9 billion active parameters to balance reasoning capabilities with computational efficiency. Native 2-bit quantization enables the model to operate within a 24GB memory footprint on supported NVIDIA systems. Its agentic capabilities include web research, code generation, software debugging, information retrieval, and multistep task execution. The model can be integrated with local AI agent frameworks and development tools to complete assignments without sending application workloads to external inference services. Bolt E4B is optimized for fast conversational responses, multistep interactions, and embedded AI experiences such as virtual assistants and interactive game characters. NVIDIA supports local deployment of the Bolt family across compatible GeForce RTX, RTX PRO, DGX Spark, and Jetson hardware, depending on the model variant. Bolt 74B-A9B is available with open weights through Hugging Face and supports inference tools including llama.cpp, Ollama, LM Studio, Unsloth, and vLLM.

Mistral Small 3.1 represents a cutting-edge, multimodal, and multilingual AI model that has been released under the Apache 2.0 license. This upgraded version builds on Mistral Small 3, featuring enhanced text capabilities and superior multimodal comprehension, while also accommodating an extended context window of up to 128,000 tokens. It demonstrates superior performance compared to similar models such as Gemma 3 and GPT-4o Mini, achieving impressive inference speeds of 150 tokens per second. Tailored for adaptability, Mistral Small 3.1 shines in a variety of applications, including instruction following, conversational support, image analysis, and function execution, making it ideal for both business and consumer AI needs. The model's streamlined architecture enables it to operate efficiently on hardware such as a single RTX 4090 or a Mac equipped with 32GB of RAM, thus supporting on-device implementations. Users can download it from Hugging Face and access it through Mistral AI's developer playground, while it is also integrated into platforms like Gemini Enterprise Agent Platform, with additional accessibility on NVIDIA NIM and more. This flexibility ensures that developers can leverage its capabilities across diverse environments and applications.

Mistral Medium 3 is an innovative AI model designed to offer high performance at a significantly lower cost, making it an attractive solution for enterprises. It integrates seamlessly with both on-premises and cloud environments, supporting hybrid deployments for more flexibility. This model stands out in professional use cases such as coding, STEM tasks, and multimodal understanding, where it achieves near-competitive results against larger, more expensive models. Additionally, Mistral Medium 3 allows businesses to deploy custom post-training and integrate it into existing systems, making it adaptable to various industry needs. With its impressive performance in coding tasks and real-world human evaluations, Mistral Medium 3 is a cost-effective solution that enables companies to implement AI into their workflows. Its enterprise-focused features, including continuous pretraining and domain-specific fine-tuning, make it a reliable tool for sectors like healthcare, financial services, and energy.

NVIDIA NeMo LLM offers a streamlined approach to personalizing and utilizing large language models that are built on a variety of frameworks. Developers are empowered to implement enterprise AI solutions utilizing NeMo LLM across both private and public cloud environments. They can access Megatron 530B, which is among the largest language models available, via the cloud API or through the LLM service for hands-on experimentation. Users can tailor their selections from a range of NVIDIA or community-supported models that align with their AI application needs. By utilizing prompt learning techniques, they can enhance the quality of responses in just minutes to hours by supplying targeted context for particular use cases. Moreover, the NeMo LLM Service and the cloud API allow users to harness the capabilities of NVIDIA Megatron 530B, ensuring they have access to cutting-edge language processing technology. Additionally, the platform supports models specifically designed for drug discovery, available through both the cloud API and the NVIDIA BioNeMo framework, further expanding the potential applications of this innovative service.