Best Encryption Software for Microsoft 365

Find and compare the best Encryption software for Microsoft 365 in 2026

Use the comparison tool below to compare the top Encryption software for Microsoft 365 on the market. You can filter results by user reviews, pricing, features, platform, region, support options, integrations, and more.

  • 1
    Files.com Reviews
    Top Pick

    Files.com

    Files.com

    $199/month/10 users
    330 Ratings
    See Software
    Learn More
    6,000+ companies trust Files.com to automate and secure business critical transfers. We obsess about security, compliance, reliability, and performance so your critical business processes just work every time. Easily manage any transfer flow without writing scripts or code, and onboard workloads and partners effortlessly. We support standard file transfer protocols (FTP, SFTP, AS2) for working with external partners and also provide native apps for high performance internal transfers. As a fully Cloud-Native SaaS, there are no servers for you to buy or maintain, there is no installation required, and high availability and redundancy are built in and free. Our InfoSec Program is audited annually by Kirkpatrick Price, a leading information security CPA firm. Our audit covers the scope of the entire Files.com business (not just datacenter operations) and names Files.com specifically. Beware of smaller competitors who try to pass off someone else’s audit as their own. Technical capabilities include encryption at-rest and in-transit, four types of two-factor authentication, nine enterprise identity (SSO) integrations, configurable password and session policies, and a perfect “A+” score from Qualys SSL Labs.
  • 2
    SharePass Reviews
    Top Pick
    Secrets and confidential information should be shared with care. SharePass is the perfect solution for businesses who want to automate secret management and keep it all in one place securely online or on your phone - no matter where you're at. SharePass enables you to send encrypted links from sender to receiver with various settings. The settings include expiration restrictions, availability and IP restrictions which can be set through our patent-pending platform-independent sharing system. With its cutting-edge encryption and security measures, SharePass is committed to keeping your personal information safe. We cannot see what your secrets are, the only people who know are the ones sharing them. In this era of identity theft, SharePass will protect you and prevent your data from leaking to the dark web by eliminating all evidence that it was ever there. SharePass supports single sign-on with Office365, Google Workspace, MFA & integration for Yubikeys so maximum security is guaranteed.
  • 3
    N-able Mail Assure Reviews
    Top Pick
    N-able Mail Assure, a cloud-based email security system, provides advanced threat protection for both inbound and outbound emails using collective threat intelligence, long-term email archive, and 24/7 email continuity. The service offers multi-tenant web-interfaces with predefined settings, reporting and views that allow for control and visibility over all email flows. N-able Mail Assure's proprietary technology uses input from large volumes of email data to feed the Intelligent Protection and Filtering engine. This, combined with real-time pattern threat detection leveraging a variety if filtering technologies, helps protect against spam, viruses and phishing attacks as well as impersonation, malware and other email-borne threats.
  • 4
    Tresorit Reviews
    Top Pick
    Tresorit is a zero‑knowledge, end‑to‑end encrypted cloud collaboration platform designed for individuals and organizations that need uncompromising data security. It enables users to securely store, sync, and share sensitive files while ensuring that only the data owner and explicitly authorized recipients can access the content. Files are encrypted on the user’s device before upload, and encryption keys are never available to Tresorit, eliminating the risk of provider‑side data access or exposure. Built as a privacy‑first alternative to conventional cloud services, Tresorit supports secure internal collaboration as well as controlled external data exchange. Teams can share files and folders with granular permission settings, revoke access at any time, and monitor activity to maintain full visibility and control. External sharing is protected through encrypted links and secure email delivery, replacing risky attachments and uncontrolled file transfers. Tresorit also enables secure, long‑term collaboration with clients and partners through encrypted data rooms that centralize documents, tasks, and approvals in a single protected workspace. Integrated digital signatures allow documents to be reviewed and signed without leaving the encrypted environment, preserving security throughout the entire document lifecycle. With advanced admin controls, auditability, and configurable data residency options, Tresorit is built to support strict regulatory and compliance requirements. By combining strong security with ease of use, Tresorit allows organizations to collaborate productively while maintaining confidentiality, ownership, and trust over their most sensitive data.
  • 5
    BitLocker Reviews
    BitLocker Drive Encryption serves as a crucial data security feature, seamlessly integrated into the operating system, designed to combat risks associated with data theft or exposure due to lost, stolen, or improperly retired computers. The most robust protection is achieved when BitLocker is paired with a Trusted Platform Module (TPM) version 1.2 or higher, a hardware element that many modern computers come equipped with. This TPM collaborates with BitLocker to safeguard user data and verify that the computer remains untampered while offline. For machines lacking a TPM version 1.2 or more advanced, BitLocker can still encrypt the Windows operating system drive, but this setup necessitates the user to utilize a USB startup key to power on the computer or wake it from hibernation. Since the introduction of Windows 8, users can also opt for an operating system volume password to secure the operating system volume on computers without a TPM. This additional flexibility enhances usability while maintaining security standards.
  • 6
    WinZip SafeShare Reviews

    WinZip SafeShare

    WinZip

    $34.95 one-time payment
    Experience a contemporary method of sharing that prioritizes confidence and security in an easy-to-use platform designed for simplicity. This robust tool empowers users to share, compress, and encrypt files seamlessly through a straightforward interface. Effortlessly distribute files to multiple destinations while benefiting from enhanced security measures, including military-grade encryption and time-sensitive sharing options. Take advantage of expanded cloud services featuring providers like OpenStack, SwiftStack, Alibaba, Wasabi, HP, Oracle, Azure, WebDAV, CenturyLink, IONOS, and OVH. Merge several PDF documents into a single file for convenient saving, zipping, or sharing purposes. Optimize your workflow by sharing directly through Slack IM, and effectively manage files shared via WinZip or ZipShare. Furthermore, users can open, view, re-share, or remove files at their discretion, while keeping track of Zip files shared through WinZip or ZipShare. Enhance your communication by emailing anyone directly from WinZip, incorporating contacts from various supported sources into a unified address book for easier access. This streamlined approach not only simplifies sharing but also enhances productivity across your collaborative efforts.
  • 7
    ESET PROTECT Elite Reviews

    ESET PROTECT Elite

    ESET

    $275 one-time payment
    ESET PROTECT Elite serves as a top-tier cybersecurity platform designed for enterprises, seamlessly combining extensive detection and response capabilities with a robust multilayered defense system. Utilizing cutting-edge techniques like adaptive scanning, machine learning, cloud sandboxing, and behavioral analysis, it effectively combats zero-day vulnerabilities and ransomware threats. The solution delivers modern endpoint protection for both computers and mobile devices, along with server security that ensures real-time data safety and mobile threat defense. Additionally, it incorporates full disk encryption, which aids organizations in meeting data protection compliance requirements. ESET PROTECT Elite also boasts powerful email security features that encompass anti-phishing, anti-malware, and anti-spam measures, while providing protection for cloud applications such as Microsoft 365 and Google Workspace. Its vulnerability management and patch capabilities automate the identification and remediation of security flaws across all endpoints, fostering a proactive approach to cybersecurity. Overall, ESET PROTECT Elite is a comprehensive solution that addresses the evolving challenges of modern cybersecurity threats.
  • 8
    IBM Guardium Data Encryption Reviews
    Safeguard your file and database information from potential abuse while ensuring compliance with both industry standards and governmental regulations by utilizing this comprehensive suite of integrated encryption solutions. IBM Guardium Data Encryption offers a cohesive set of products that share a unified infrastructure. These scalable solutions incorporate encryption, tokenization, data masking, and key management features, essential for protecting and regulating access to databases, files, and containers across hybrid multicloud environments, thereby securing assets located in cloud, virtual, big data, and on-premises settings. By effectively encrypting file and database data through functionalities like tokenization, data masking, and key rotation, organizations can successfully navigate compliance with various regulations, including GDPR, CCPA, PCI DSS, and HIPAA. Moreover, the extensive capabilities of Guardium Data Encryption—including data access audit logging and comprehensive key management—further assist organizations in meeting critical compliance requirements, ensuring that sensitive data remains protected at all times. Ultimately, implementing such robust encryption measures not only enhances security but also builds trust among stakeholders.
  • 9
    WinZip SafeMedia Reviews
    Employees require the ability to carry digital data with them at all times, and it is essential for businesses to guarantee the security of that information. WinZip SafeMedia allows users to efficiently and securely store, manage, and transfer files using removable media, such as CDs, DVDs, and USB drives, while also enabling IT administrators to implement robust security protocols that safeguard against both online and offline threats. Organizations can customize their security policies to meet specific requirements, adjusting settings for individual users or groups and keeping an eye on activity as necessary. By utilizing user-friendly features like drag and drop alongside automated security functions, the solution ensures that end users remain productive without facing unnecessary obstacles. In addition, the software employs FIPS 140-2 compliant and FIPS 197 certified encryption and compression techniques to secure data stored on removable devices. With top-tier encryption methods in place, businesses can protect sensitive information while enjoying the benefits of flexible storage options and centralized management. This comprehensive approach to data security not only enhances protection but also fosters a culture of trust within the organization.
  • 10
    OpenText ZENworks Full Disk Encryption Reviews
    OpenText ZENworks full disk encryption allows you to centrally enforce policies that encrypt entire hard drives on Windows 7, Windows 8 and Windows 10 machines within your organization. You can manage them with the same web-based interface and adaptive agent you use for other ZENworks Products. Encrypting your entire hard drive is a proven way to protect company data. Ensure that devices encrypted across the enterprise are easy to manage. You can remotely unlock devices protected by full disk-encryption and keep users productive when they work remotely. You must comply with government regulations and industry guidelines to protect patient and customer data. Use your experience with ZENworks in order to reduce the costs of implementing Full Disk Encryption.
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