Compare Holo4 vs. VSI HoloMedicine in 2026

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Description

Holo4 is H Company's series of generalist computer-use and agentic AI models built to perform multi-step work across software interfaces. It is available as Holo4 27B, a dense 27-billion-parameter model, and Holo4 35B-A3B, a Mixture-of-Experts model containing 35 billion total parameters with 3 billion active. Holo4 can interact with applications by clicking and typing through graphical interfaces, writing and executing code, or calling MCP and API tools. The same model can operate across desktops, websites, Android devices, code sandboxes, and business APIs without requiring developers to select a separate specialized model for each environment. H Company trained Holo4 using 127 billion supervised fine-tuning tokens, with approximately three-quarters consisting of successful agentic trajectories spanning desktop, web, MCP/API, and mobile tasks. Reinforcement learning then trained separate experts for desktop and web interaction and for terminal, MCP, and API work before merging them into a single model. Holo4 27B scored 85.2% on OSWorld, 61.7% on OSWorld 2.0, 45.4% on AutomationBench, and 85.1% on AndroidWorld in the evaluations reported by H Company. The models support a 256K context window, with the 27B model positioned for greater accuracy on long multi-step tasks and the 35B-A3B version positioned as a faster and less expensive alternative. Holo4 is available through a hosted API and downloadable model weights, enabling developers and enterprises to build agents that perform workflows spanning multiple applications and interaction methods.

Description

VSI HoloMedicine® by apoQlar is an innovative software platform that utilizes Microsoft HoloLens 2 technology to revolutionize medical imaging, clinical processes, and educational methods within a groundbreaking 3D mixed reality framework. Move beyond traditional textbooks and explore VSI’s extensive digital repository of authentic medical images, case studies, and volumetric 3D mixed reality lectures. Enhance your students' understanding of structural relationships and anatomy by providing them with advanced segmentation tools. This platform allows users to engage with real human anatomy cases and intricate pathology visuals in an unprecedented way. By integrating these tools, you can make anatomical comprehension much more accessible for your learners. Our approach to transforming medicine is comprehensive, as we have redefined clinical workflows to utilize the potential of medical mixed reality effectively. Our dedicated medical advisory board, consisting of nearly 30 specialized physicians from around the world, guides our research and development efforts to guarantee clinical accuracy and relevance. With this collaboration, we aim to ensure that the advancements we make are truly beneficial to the medical community.