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Description

Folklore serves as a research-exclusive platform offered by Helena Bioinformatics for the interpretation of clinical variants. It assists genomic professionals in analyzing public variant data, literature, clinical claims, population statistics, and pertinent guidelines through an organized process. Additionally, Folklore features a public read-only MCP adapter designed for the discovery of evidence via agent-based methods. It is not intended to provide diagnoses, suggest treatment options, or substitute for expert evaluations. This platform is specifically designed for use by clinical genomics teams, molecular diagnostic facilities, researchers, bioinformaticians, and scientists specializing in variants. Overall, Folklore aims to enhance the efficiency and accuracy of variant interpretation in the clinical setting.

Description

VSClinical facilitates the clinical analysis of genetic variants in accordance with ACMG and AMP guidelines. Its structured workflow supports adherence to the American College of Medical Genetics (ACMG) standards, which are essential for identifying and categorizing pathogenic variants related to inherited disease risk, cancer susceptibility, and rare disease diagnosis. The combined ACMG/AMP guidelines for variant interpretation establish a framework for scoring variants and categorizing them into one of five classification levels. Implementing these guidelines necessitates a thorough examination of annotations, genomic contexts, and pre-existing clinical insights for each variant. VSClinical streamlines this process by offering a customized workflow that evaluates each relevant criterion and supplies comprehensive bioinformatics, literature references, and clinical knowledgebase evidence to aid in the scoring and interpretation of variants. This innovative approach is designed to enhance the efficiency of variant scientists as they navigate the complexities of variant processing and analysis. Overall, VSClinical stands out as a vital tool for accelerating the understanding and classification of genetic variants in clinical settings.

API Access

Has API

API Access

Has API

Screenshots View All

No images available

Screenshots View All

Integrations

GenomeBrowse
VarSeq

Integrations

GenomeBrowse
VarSeq

Pricing Details

No price information available.
Free Trial
Free Version

Pricing Details

No price information available.
Free Trial
Free Version

Deployment

Web-Based
On-Premises
iPhone App
iPad App
Android App
Windows
Mac
Linux
Chromebook

Deployment

Web-Based
On-Premises
iPhone App
iPad App
Android App
Windows
Mac
Linux
Chromebook

Customer Support

Business Hours
Live Rep (24/7)
Online Support

Customer Support

Business Hours
Live Rep (24/7)
Online Support

Types of Training

Training Docs
Webinars
Live Training (Online)
In Person

Types of Training

Training Docs
Webinars
Live Training (Online)
In Person

Vendor Details

Company Name

Helena Bioinformatics

Country

Bulgaria

Website

folklore.helena.bio

Vendor Details

Company Name

Golden Helix

Founded

1998

Country

United States

Website

www.goldenhelix.com/products/VarSeq/vsclinical.html

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