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Description
Mantarray revolutionizes the early phases of preclinical drug testing by integrating functional data with advanced technologies. By enabling simultaneous analysis of 3D engineered muscle tissues that exhibit adult-like functional characteristics, Mantarray facilitates the identification, safety assessment, and effectiveness evaluation of new therapeutics. With an impressive tissue formation success rate exceeding 95%, the Mantarray Plate Kit ensures consistent and reproducible engineered tissues across 24 wells. This innovative platform offers a user-friendly, scalable, and adaptable solution that empowers researchers to analyze 3D tissues in vitro right within their labs. Early adopters can take advantage of this groundbreaking instrument. The Mantarray system employs a unique magnetic sensing method that accurately detects the contractions of engineered muscle tissues (EMTs), allowing users to assess the contractility of 24 tissues simultaneously and in real time, greatly enhancing throughput. Moreover, the accompanying software simplifies the process by eliminating the need for manual contractility calculations, thus streamlining the research workflow. Overall, Mantarray not only improves the efficiency of drug discovery but also enhances the reliability of data obtained during preclinical studies.
Description
The foundational aspect of our immunotherapy approach lies in our comprehension of antigens and neoantigens, particularly in identifying which variations will be transcribed, translated, processed, and subsequently displayed on the surface of cells via Human leukocyte antigen (HLA) molecules, thus making them recognizable to T cells. We achieve this by employing Gritstone EDGETM, a unique platform powered by machine learning. Creating cancer immunotherapies that incorporate tumor-specific neoantigens proves challenging, mainly because tumors consist of numerous mutations, yet only a fraction of these lead to genuine tumor-specific neoantigens. To tackle this complexity, we have developed EDGE's cutting-edge integrated neural network model, trained with millions of data points gathered from a diverse range of tumor and normal tissue samples across various patient ancestries. This extensive training allows us to enhance the accuracy of neoantigen identification and improve the effectiveness of our immunotherapy strategies.
API Access
Has API
API Access
Has API
Integrations
No details available.
Integrations
No details available.
Pricing Details
No price information available.
Free Trial
Free Version
Pricing Details
No price information available.
Free Trial
Free Version
Deployment
Web-Based
On-Premises
iPhone App
iPad App
Android App
Windows
Mac
Linux
Chromebook
Deployment
Web-Based
On-Premises
iPhone App
iPad App
Android App
Windows
Mac
Linux
Chromebook
Customer Support
Business Hours
Live Rep (24/7)
Online Support
Customer Support
Business Hours
Live Rep (24/7)
Online Support
Types of Training
Training Docs
Webinars
Live Training (Online)
In Person
Types of Training
Training Docs
Webinars
Live Training (Online)
In Person
Vendor Details
Company Name
Curi Bio
Founded
2015
Country
United States
Website
www.curibio.com/mantarray
Vendor Details
Company Name
Gritstone bio
Founded
2015
Country
United States
Website
gritstonebio.com/scientific-platform/