Best Antivirus Software for Microsoft 365

Find and compare the best Antivirus software for Microsoft 365 in 2026

Use the comparison tool below to compare the top Antivirus software for Microsoft 365 on the market. You can filter results by user reviews, pricing, features, platform, region, support options, integrations, and more.

  • 1
    Trend Micro Cloud App Security Reviews
    Improve the security of cloud platforms like Office 365 and Google Workspace by utilizing sandbox malware analysis to combat ransomware, business email compromise (BEC), and other sophisticated threats. While Office 365 comes with built-in security that addresses known antivirus issues, it is important to recognize that a staggering 95% of modern malware targets a single device and evades conventional antivirus methods. By employing direct cloud-to-cloud integration through APIs, organizations can bolster their defenses seamlessly without the hassle of complicated setups. This integration is designed for quick and automatic deployment, requiring no software installation, user configuration adjustments, proxy deployment, or changes to MX records, allowing businesses to enhance their security posture effortlessly and effectively. Additionally, implementing these advanced security measures not only helps in mitigating risks but also ensures a smoother user experience across cloud services.
  • 2
    ESET PROTECT Elite Reviews

    ESET PROTECT Elite

    ESET

    $275 one-time payment
    ESET PROTECT Elite serves as a top-tier cybersecurity platform designed for enterprises, seamlessly combining extensive detection and response capabilities with a robust multilayered defense system. Utilizing cutting-edge techniques like adaptive scanning, machine learning, cloud sandboxing, and behavioral analysis, it effectively combats zero-day vulnerabilities and ransomware threats. The solution delivers modern endpoint protection for both computers and mobile devices, along with server security that ensures real-time data safety and mobile threat defense. Additionally, it incorporates full disk encryption, which aids organizations in meeting data protection compliance requirements. ESET PROTECT Elite also boasts powerful email security features that encompass anti-phishing, anti-malware, and anti-spam measures, while providing protection for cloud applications such as Microsoft 365 and Google Workspace. Its vulnerability management and patch capabilities automate the identification and remediation of security flaws across all endpoints, fostering a proactive approach to cybersecurity. Overall, ESET PROTECT Elite is a comprehensive solution that addresses the evolving challenges of modern cybersecurity threats.
  • 3
    Microsoft Defender for Business Reviews
    Microsoft Defender for Business offers advanced, AI-powered cybersecurity protection built specifically for small and medium-sized organizations. It consolidates multiple security capabilities into a single solution, reducing costs while improving protection. The platform safeguards devices against ransomware, malware, phishing, and emerging threats across major operating systems. Built-in vulnerability management helps businesses discover and fix misconfigurations before they can be exploited. AI-powered endpoint detection and response works continuously to detect attacks and automatically stop them. Automated investigation and remediation reduce the need for manual security intervention. Defender for Business supports both office-based and remote employees with consistent device protection. Wizard-based setup and out-of-the-box security policies simplify deployment and management. Monthly security reports provide visibility into threats and overall security posture. Microsoft Defender for Business delivers enterprise-level protection without enterprise-level complexity.
  • 4
    Microsoft Defender for Individuals Reviews
    Experience user-friendly online security for yourself, your loved ones, and your devices with the Microsoft Defender app, which is now available for download as part of your Microsoft 365 subscription. Enjoy a unified dashboard to oversee and track your security status across all your computers and mobile devices. Safeguard your family and yourself against harmful online threats with reliable antivirus and anti-phishing measures. Receive immediate notifications along with suggested actions and tips on enhancing your online safety. Access a single interface to keep tabs on your security status, allowing you to view protection measures for both your data and devices. You can effortlessly add or remove devices as needed, ensuring peace of mind with robust malware defense for everyone in your household. Benefit from ongoing protection through consistent antivirus scans across your applications and devices. You have the ability to customize what gets scanned by marking certain apps and files as trusted. Stay informed with real-time updates regarding any changes to your family’s security situation, allowing you to act promptly and effectively. This comprehensive security solution aims to keep your online experience safe and secure at all times.
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