Zymtrace is an advanced platform for continuous profiling and observability that enables engineers to enhance the performance of contemporary computing workloads running on both CPUs and GPUs. It offers profound insights into system-level operations, revealing how applications, AI models, and infrastructure utilize computing resources, which empowers developers to pinpoint inefficiencies and performance obstacles without needing to alter their code or restart their systems. Utilizing eBPF-based profiling technology, zymtrace gathers performance data throughout the entire execution stack, ranging from high-level application code and runtime libraries to the Linux kernel and GPU instructions, thus facilitating a comprehensive analysis of diverse workloads. Furthermore, it effectively correlates GPU activities with the associated CPU code paths that initiate them, addressing a significant limitation of traditional observability tools that often regard GPUs as opaque entities, providing only superficial metrics. By bridging this gap, zymtrace enhances the overall understanding of performance dynamics in complex systems, ultimately guiding more informed optimization strategies.