Best Advanced Threat Protection (ATP) Software for Windows of 2025

Find and compare the best Advanced Threat Protection (ATP) software for Windows in 2025

Use the comparison tool below to compare the top Advanced Threat Protection (ATP) software for Windows on the market. You can filter results by user reviews, pricing, features, platform, region, support options, integrations, and more.

  • 1
    ThreatLocker Reviews
    Top Pick
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    For IT professionals to stop ransomware, you need to do more than look for threats. ThreatLocker helps you reduce your surface areas of attack with policy-driven endpoint security and change the paradigm from only blocking known threats, to blocking everything that is not explicitly allowed. Combined with Ringfencing and additional controls, you enhance your Zero Trust protection and block attacks that live off the land. Discover today the ThreatLocker suite of Zero Trust endpoint security solutions: Allowlisting, Ringfencing, Elevation Control, Storage Control, Network Access Control, Unified Audit, ThreatLocker Ops, Community, Configuration Manager and Health Center. 
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    Trustifi Reviews
    Top Pick
    Trustifi provides industry-leading email security solutions that help small, medium, and large enterprises manage threat detection, regulatory compliance and data encryption. Easily deployable on Outlook, Gmail, and any other email server via relay **Advanced Threat Protection** -Malware/ransomware virus detection and BEC attack prevention and alarms **Data Loss Prevention** --100% compliant HIPAA/HITECH and PII, GDPR. FSA, LGPD, CCPA and more **Encryption** -NSA-grade. Only select Enterprise customers have access the company branding and product white-labeling. One-on-one training for teams. There are many encryption requirements, so there is no one-size-fits all solution for email security. Many times, customized solutions are available on request and often free of charge.
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    SentinelOne Singularity Reviews

    SentinelOne Singularity

    SentinelOne

    $45 per user per year
    6 Ratings
    One intelligent platform. Unprecedented speeds Infinite scale. Singularity™, enables unrestricted visibility, industry-leading detection and autonomous response. Discover the power of AI powered enterprise-wide security. Singularity is used by the world's largest enterprises to detect, prevent, and respond to cyberattacks at machine speed, greater scale, with higher accuracy, across endpoints, cloud, and identities. SentinelOne's platform offers cutting-edge security by providing protection against malware, scripts, and exploits. SentinelOne's cloud-based platform is innovative, compliant with industry standards and high-performance, whether you are using Windows, Mac, or Linux. The platform is prepared for any threat thanks to constant updates, threat hunting and behavior AI.
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    ESET PROTECT Reviews
    ESET's multilayered technology protects your business endpoints, business data, and users. ESET PROTECT platform provides customizable security solutions that are easy to manage via a cloud console. Cyber risk management and visibility into the IT environment. Keep one step ahead of unknown or known threats. IT staff can quickly respond to any new threats with up-to-date information. IT administrators can save time and protect themselves against future attacks by using predefined policies and automating tasks. Scheduled reporting and dozens customizable templates make it easy to meet reporting requirements. A malicious email might be opened by a user in your network that contains ransomware. Programmers who use code on their work computers may create false positives from compiling software.
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    Symantec Endpoint Protection Reviews
    Symantec Endpoint Security is the best integrated endpoint security platform available. Symantec Endpoint Security is available as an on-premises, hybrid or cloud-based platform. It protects both your mobile and traditional endpoint devices and uses artificial intelligence (AI), to optimize security decisions. Unified cloud-based management makes it easy to detect, protect and respond to advanced threats that target your endpoints. Keep your business running. Compromised endpoints can be disruptive to your business. Innovative attack prevention and attack surfaces reduction provide the best security throughout the attack life cycle (e.g. stealthy malware and credential theft, fileless and "living off the land". Avoid the worst-case scenario. Full-blown breaches are CISOs worst nightmare. Provide detection and remediation for persistent threats using sophisticated attack analytics and prevention from AD credential theft.
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    Trellix Endpoint Security (HX) Reviews
    Trellix Endpoint Security HX performs targeted, fast forensic investigations on thousands of endpoints. Protect and empower your employees with an integrated security system that protects all endpoints. Trellix Endpoint Security Solutions apply proactive threat intelligence, defenses and protections across the entire attack cycle to keep your organization more resilient and safer. Keep your endpoints safe in today's dynamic threats landscape. Discover how our integrated suites of endpoint protection technology can help you monitor threats and avert them by combining machine learning and actionable intelligence. Endpoint security is a practice that involves safeguarding data and workflows on the devices that connect to the network. Endpoint protection platforms (EPPs) examine files as they enter your network.
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    WorkDesk Reviews

    WorkDesk

    SquareOps

    $10 per user, per month
    You can work from anywhere, any time, and on any device. Cloud windows desktop allows remote working. It provides seamless remote access to your teams via the cloud with high security, low cost & scalability, ensuring business continuity. Advanced Threat Protection for Windows 2019 Edition is included with Virtual Cloud Desktops. These are some of the best features. WorkDesk can manage your entire remote work environment. Just a few clicks away, you will have everything you need to get started. There is no upfront cost. Pay-Per-Use: You only pay for what you use. Hourly costs are billed. You can choose any configuration. With one click, upgrade or downgrade a system configuration according to your needs. Secure Access. Secure Access is an in-built feature that can be modified to suit your needs. Cloud Storage. Cloud storage stores data, which is available from any device at any time. It's easy to use. All that is required is a click of a button.
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    Sophos Intercept X Endpoint Reviews

    Sophos Intercept X Endpoint

    Sophos

    $28 per user per year
    With remote response capabilities and powerful querying, you can take threat hunting and IT security operations up to the next level. Ransomware file protection, automatic recovery, and behavioral analysis are all available to stop ransomware attacks and boot record. Deep Learning Technology Artificial intelligence integrated into InterceptX that detects known and unknown malware, without relying upon signatures. Blocking exploits and techniques that are used to distribute malware, steal credentials and escape detection will deny attackers. An elite team of threat hunters and experts in response to take targeted actions for you to eliminate even the most sophisticated threats. Active adversary mitigation stops persistence on machines, credential theft protection and malicious traffic detection.
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    iPrism Web Security Reviews
    iPrism Web Security combines fine-grained content filtering with threat detection and mitigation methods to provide powerful protection against Advanced Persistent Threats (botnets, viruses, and others). iPrism Web Security is easy to use and "set it and forget". It is self-contained to provide advanced threat protection, policy enforcement, and requires almost no maintenance. Our comprehensive reporting makes managing your network easy. iPrism employs a unique combination of iGuard's automated intelligence and human analysis to block malware, Crypto-Locker, and other inappropriate sites. It improves user productivity by reducing latency and false negative rates. This innovative approach ensures that you have the most up-to-date, advanced web protection available 24/7 and is supported by world-class customer service.
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    Microsoft Defender for Endpoint Reviews
    You can gain an edge over sophisticated threats such as ransomware and nation state attacks. To prioritize risks and improve your security posture, give time back to defenders. You can move beyond endpoint silos and improve your security by establishing a foundation for XDR (zero trust) and other principles. Microsoft Defender for Endpoint provides industry-leading endpoint protection for Windows, macOS Linux, Android, iOS and network devices. It helps you quickly stop attacks, scale security resources, and improve your defenses. It is delivered at cloud scale with built-in AI which analyzes the largest threat intelligence in the industry. Our comprehensive solution allows you to discover all endpoints and network devices in your environment. It provides endpoint protection, endpoint protection, mobile threat defense, endpoint detection, and response (EDR) all in one, unified platform.
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    Juniper Advanced Threat Protection Reviews
    The threat intelligence hub of your network is Juniper Advanced Threat Prevention. It has a number of advanced security services built-in that utilize AI and machine learning in order to detect attacks early and optimize network policy enforcement. Juniper ATP can be deployed as a cloud enabled service on an SRX Series Firewall, or as a local virtual appliance. It detects and blocks zero-day and commodity malware in files, IP traffic and DNS requests. The service analyzes and distributes intelligence from network traffic, connected devices (including IoT), and encrypted and decrypted traffic. This reduces your attack surface and helps you avoid breaches. Automatically discover and mitigate zero-day and known threats. Identify and stop threats hidden within encrypted traffic, without decrypting. Detect targeted attacks against your network including high-risk devices and users, and automatically mobilize defenses.
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    SandBlast Network Reviews

    SandBlast Network

    Check Point Software Technologies

    Cyber attacks are becoming more complex and difficult to detect. This makes security more difficult and tedious, affecting user workflows. SandBlast Network offers the best zero-day protection, while reducing security overheads and ensuring business productivity. SandBlast Network offers the best zero-day protection available in the industry. It also reduces administration overhead and ensures that businesses are productive. Unknown cyber threats are prevented by AI and threat intelligence. One click setup with out-of the-box profiles optimized to business needs. It is a prevention-first strategy that has no impact on the user experience. Humans are the weakest link of the security chain. Pre-emptive user protections prevent threats from reaching users, regardless of user activity (browsing or email). Real-time threat intelligence, derived from hundreds and millions of sensors around the globe.
  • 13
    FortiSandbox Reviews
    Antivirus tools provided reasonable protection against viruses, unlike previous generations that were simple and low-volume. Modern malware uses new techniques, such as exploits. An attacker can exploit a vulnerability in legitimate software to cause abnormal behavior. An attack that exploits an unknown software vulnerability is called a zero-day or 0-day attack. Before sandboxing, there was no effective way to stop it. A malware sandbox is a system that restricts an application's actions, such as opening Word documents, to an isolated environment. The sandbox examines the dynamic behavior and interactions of applications in a pseudo-user environment to uncover malicious intent.
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