An essential element of a zero-trust framework is the protection of the workplace that serves as the connection point for all users and devices. The Cisco Identity Services Engine (ISE) facilitates a flexible and automated method for enforcing policies, streamlining the provision of robust network access control. Additionally, ISE enhances software-defined access and automates the segmentation of networks across both IT and OT settings, ensuring comprehensive security. This integration allows organizations to adapt quickly to changing security requirements while maintaining a secure environment.