Amazon EC2 UltraClusters allow you to scale up to thousands of GPUs and machine learning accelerators such as AWS trainium, providing access to supercomputing performance on demand. They enable supercomputing to be accessible for ML, generative AI and high-performance computing through a simple, pay-as you-go model, without any setup or maintenance fees. UltraClusters are made up of thousands of accelerated EC2 instance co-located within a specific AWS Availability Zone and interconnected with Elastic Fabric Adapter networking to create a petabit scale non-blocking network. This architecture provides high-performance networking, and access to Amazon FSx, a fully-managed shared storage built on a parallel high-performance file system. It allows rapid processing of large datasets at sub-millisecond latency. EC2 UltraClusters offer scale-out capabilities to reduce training times for distributed ML workloads and tightly coupled HPC workloads.