Nue is a streamlined, standards-driven web development framework that prioritizes progressive enhancement, clear separation of concerns, and semantic web design, making it easier for developers to create contemporary websites and applications. By integrating a static site generator with capabilities for both multi-page and single-page applications, it allows for the usage of advanced Markdown, HTML-first UI assembly, URL-centric state management, and modern CSS for design and styling, all while maintaining clean markup optimized for accessibility and search engine optimization. The ecosystem is compact, approximately 1MB in size, yet it includes features such as universal hot reload, single-page application development, dynamic islands, seamless view transitions, content collections, TypeScript support, CSS inlining, API routing, and full-stack previews, minimizing the need for extensive tooling or intricate configurations. Nue also effectively delineates content, layout, and logic, facilitating independent work among designers, content strategists, and developers. Furthermore, this approach fosters collaboration and enhances productivity within teams, allowing for a more efficient development process overall.