My mouse doesn't feel right on Linux, I would switch if it weren't for that.
Maybe your mouse is just shy. Have you tried introducing it slowly?
Shoot it, blow a fire extinguisher at it, pee on it, use compressed air, drop it on the floor, EMP it... whatever.
I can assure you that peeing on a computer will not necessarily kill it.
But it might kill you.
"When the going gets tough, the tough get empirical." -- Jon Carroll