Since the moderation system started using AJAX, it became really annoying.
Guys! It is a really bad idea to submit moderation on "onchange" event on the combobox. It is really easy to choose the wrong option and there is no easy way to cancel wrong moderation. Misclick is actually only the part of the issue: if the combobox has focus, pressing Up or Down changes its value thus moderating the comment.
So, please, make a nice "OK" button next to the moderation combobox and bind the required event to it, rather then the box itself.