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Medicine

Creating "Homo Minutus" — a Benchtop Human To Test Drugs 49

Science_afficionado (932920) writes "Vanderbilt University scientists reported significant progress toward creating 'homo minutus' — a benchtop human — at the Society of Toxicology meeting on Mar. 26 in Phoenix. The advance is the successful development and analysis of a human liver construct//organ-on-a-chip that responds to exposure to a toxic chemical much like a real liver. The achievement is the first result from a five-year, $19 million multi-institutional effort led by Los Alamos National Laboratory (LANL), to develop four interconnected human organ constructs — liver, heart, lung and kidney — that are based on a highly miniaturized platform nicknamed ATHENA (Advanced Tissue-engineered Human Ectypal Network Analyzer). The project is supported by the Defense Threat Reduction Agency. Similar programs to create smaller-scale organs-on-chips are underway at the Defense Advanced Research Projects Agency and the National Institutes of Health."

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