If you're interested I can drop you an invitation code to
(hit the button to request a pre-launch invite and then ping me on twitter or similar to identify yourself)
It's free and runs in the browser without plugins (but you can export your data locally, an offline mode is fairly straightforward, just not a high priority at this point) - it's aimed more at when you move your files onto the web for storage, but it can handle local files within browser sandbox limitations.
It mixes note-taking, bookmarking, annotation and tagging, reminders, and notifications, but then also features smart integration with other sources, so it knows about things like wikipedia and twitter and actively integrates with such sources via plugins (I'm toying with the idea of a Mendeley plugin).
The aim is not so much to replace lots of other services, but to sit on top of them and give you a smart integration layer, so rather than building a static "bucket" as a repository, you can build something that is more active, and lets you get on with what you need to do with your resources rather than constantly going back and checking them.
And I'm UK based so you may find some of the spellings familiar ("organise"!!)