LyX is a project that I'm very fond of. It doesn't follow the WYSIWYG model at all. Instead, it leverages TeX's different way of thinking about document creation entirely; separate the data from the presentation and manage the creation of both separately. The whole idea is to concentrate on the task of writing without getting distracted by constant re-formatting challenges. It works quite well once you learn to relax and not obsess over every paragraph and image placement while you're writing.
Frankly, I think LyX creates some of the most beautiful printed documentation I've ever seen. Sadly, it doesn't do so well at e-publishing yet. I have hopes that will change, though. I would love to use it to handle all of my document creation needs.
As it is, I end up writing in LyX, exporting to