The problem there is that the advertisers forgot the old adage "you don't shit where you eat".
If they had simply shown a few ads and made sure their servers were up to the task, few if any would have even bothered with ad-blockers. But no, They had to plaster the page with jumping singing dancing ads that pop up and pop under and triple (or worse) the page load time. Then to top it off, they didn't even bother to make sure the ads weren't drive-by viruses or illegal scams.
Since all of that wasn't enough, they decided to also become internet stalkers.
It's only natural that people came to consider most any ad they see on the web to be a probable scam and to run ad blockers to avoid the assault on their senses and more that a few infections as well.
Then finally, when given a chance to restore some tiny shred of good will, they decided to ignore DNT.