I routinely stop alien invasions. Their lazors are no match for my hands (and let's not mention my other weapon... in my pants).
Your move NSA - what have you done lately?
I swear, read the fucking summary before commenting! Changing OS is not an option, changing platform (and therefore "the way the computer is used") is not an option, abandoning MS Office is not an option and OP is not asking for recommendations on an Internet Security package.
(Also, NoScript is really problematic for "normal people", so stop recommending it. AdBlock takes away most nasty things anyway)
The sooner you fall behind, the more time you have to catch up.