"The criticism from the Chief Inspector of Nuclear Installations was withering: “The Plant was operated in a culture that seemed to allow instruments to operate in alarm mode rather than questioning the alarm and rectifying the relevant fault.” "
Anyone who actually works for a living will understand how common this is. For most workers, every new safety procedure is one more opportunity to take a nap on company time, or one more annoyance to be worked around or ignored. I've had jobs where other workers complained if I wore safety glasses because it made them look bad for not wearing theirs. The only reason I don't face significant social pressure to ditch my glasses is because I need them to see - even though they have successfully protected my eyes from flying debris on numerous occasions.
There is no solution for human carelessness, laziness, or obstinacy, except to remove the humans entirely - or at least human decision-making. Changing to equipment and materials that are inherently safer works, but safety guards on equipment will be hastily removed the first moment a worker has an excuse - even the appearance of a malfunction will do - and they will not be replaced. In fact, they will be discarded immediately to ensure that they cannot be replaced. A very strict safety program may reduce such things a little, but the pressure must be constant.
If systems can be fully automated, and put under the supervision of a perfectionist, that may be sufficient. Otherwise, it is a good thing that nuclear plants and most everything life critical is over-engineered.