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Comment Re:For what purpose? (Score 3, Insightful) 343

What about police guards at G8 protests, certain sporting events? Surely by turning up they are assuming guilt. Never mind that there is a 100% occurrence of violent incidents and they would be derelict in duty by staying home... What about bobbies on the beat in rough neighbourhoods where someone gets stabbed every week? Are they being offensively oppresive? Stop being so asinine.

Comment Re:please change your sig (Score 1) 490

Do I deserve the label of "Transphobe" - a term I've never seen or thought about before? Like many others, this intriguing tangential comment thread is the first window I've had to an unusual new world of personal sensitivity, yet another way I could accidentally offend someone I don't personally know with my assumptions about the world.

Every time I talk about my friends, parents, pets in casual conversation with a new acquaintance, I know there's a small chance that they might have suffered though the death of same, and that I'm unintentionally torturing them. Do I stop doing it to everyone new "just in case"? No. I'd be a ball of nerves otherwise, trying to remember every single thing I could say that people might get upset about, some of which contradict each other.

So I guess what I'm saying is that I might deserve your label. I don't have the intention to offend, but I've made a decision to continue living in happy ignorance, and not to invest a lot of my time and effort into making certain changes that would presumably benefit you if we ever happened to chitchat in a shop, or something. I can only apologise, and offer what I think the silent majority, the kindly but blundering everyman thinks about it all.

Comment Re:An another assumption of universality... (Score 3, Informative) 215

Claiming that research done with realistic budget limitations shames us all is asinine bullshit. You have this result, or you have nothing. This is intriguing, perhaps it merits further study, perhaps behavioural psychologists in other nations will study the locals there. Perhaps not. The only overarching conclusions were written by the five word headline, or by your own built-in summariser.

Comment Re:To those who would reply in harshness... (Score 1) 408

I'm a (professional) synthetic chemist who occasionally dabbles in the fields of pharmacology and microbiology. I know the molecular principles behind events such as protein functionality, nerve transmission, photosynthesis and other life-y things and it scares the CRAP out of me how complex and fast it is. We each of us are an entire world of kludged complexity, relying on subtle edge effects to effect thought on a timescale unimaginably slow compared to the bustle of our atoms. If a molecular interaction was two cogs turning together, each human being would be a rube goldberg machine ten light-minutes across, that took a million years just to decide whether to order a starter or not.

I also believe in a Biblical God who knows all of this, and knows how it works together, and who KNOWS MY NAME AND LOVES ME. You think I was awed before? I'm devoting my life to the study of his works, and I will never ever understand even the tiniest fraction of the possible complexity.

Less anecdotally, I agree that pseudo-science is rife, see Feynman's essay on cargo cult science. Most people don't understand you need to go out of your way to try and prove yourself wrong first.

Comment Re:Inventory (Score 2, Insightful) 450

My point was that employee theft is worse in places with poorer labour laws and oppressive workplaces, nothing more. Such extreme measures wouldn't be needed, but rather milder ones. It's a self-reinforcing problem, the more I get treated like a potential thief, the less I'm going to care about the company in return. Don't get me wrong, I think all businesses everywhere are sociopaths, but the illusion of corporate loyalty benefits everyone.

Comment Re:Inventory (Score 2, Insightful) 450

Perhaps not suspiciously regarding your employees as thieves builds, oh, I don't know, an actual environment of trust and respect? The culture of corporate sabotage certainly exists on this side of the pond, but only in occasional moments during particularly vicious company mergers or layoffs. It's much more effective here to have one or two auditors trying to spot patterns not consistent with customer-originated shrinkage, and then come in for a closer look. Even if nobody gets caught, the one guy on the take usually backs down.

Comment Re:Lameness filter (Score 5, Insightful) 274

The parent has an important point - accessibility is a two-pronged approach. Sometimes, it's appropriate to modify the world (Wheelchair Ramps, disabled bathrooms) and sometimes it's appropriate to rely on technology to help individual people (White canes, seeing-eye dogs). Mostly, they meet in the middle somewhere (hearing aid loops in cinemas are much less invasive than subtitling, and service most people with hearing difficulties). I think it's important not to get too carried away and actively hinder the lives of everyone in service of some token PC gesture that never gets used. Specifically, my office has retrofitted electric push-button door openers, which take several seconds per set of door on a very long corridor in a working environment fundamentally unsuited for wheelchair accessibility.

Comment Re:Potentially huge problem with the test (Score 1) 138

I only made the molecules and I saw a tiny corner of the industry as it was in 2008. I have general common sense in the field but I really can't say without it being my opinion.

The current thrust has always been about targeting a specific symptom (the plaques) but my feeling is that even if we get a working aB42 inhibitor, it won't stop senility. I read a few years ago about a preventative treatment that halted cognitive decay, based on a substituted ibuprofen, but I can't recall of any of the details.

Comment Re:Potentially huge problem with the test (Score 2, Informative) 138

Amyloid beta was there and it was targetable by the methodology available to drugs companies. Now, they've discovered it doesn't work, and there's a few years of lag time between findings synchronising. I don't think there are any more gamma-sec or beta-sec programs in drug discovery. Let's just hope there's another target around.

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