This is the reason why I switched to KDE from Gnome back around '05.
Gnome and its related applications presume to know how best to use an application, regardless of peoples' varying workflows and, by extension, their preferred configuration.
To sum up my experiences with Gnome:
1) Find something that doesn't act how you want it to
2) Open configuration menu for that particular application / OS function
3) Find out that the configuration menu only has one checkbox, and it's not for the feature you want to change.
4) Ragequit
Conversely, of course, KDE is more along the lines of:
1) Find something that doesn't act how you want it to
2) Open configuration menu for that particular application / OS function
3) Tab through multiple pages of options until you find what you want
4) Celebrate
Honestly, I'd rather have to wade through 100 pages of configuration options to find what i want than to not be able to find it at all. That said, there are some Gnome apps that have 100,000 options, and some equivalent KDE apps that have 1 or 2; however, I'm speaking more to the overall design ideology of the Gnome system.
On a side note, I'm amazed that there is actual honest discourse going on in this thread. Why, even just a few years ago, one couldn't shout "Gnome!" or "KDE!" without starting an all-out flamewar. This thread seems, in comparison, fairly civil.