Where I feel the problem lies is this: The game seems to ignore CHARACTER dexterity in combat, and instead relies more on PLAYER dexterity. There is a difference. I am not in the peak of health (as my character is supposed to be) nor am I trained in combat (as my Fighter is supposed to be). I am also constrained by a very artificial interface (KBD/mouse/monitor) instead of being actually in the room. The role-playing implies that I am NOT my character and he is not me, but that the character is a separate role that I am playing, and should be as little restricted by my abilities as possible.
Maybe it's just me, but RPGs just shouldn't be action/FPS (first person spellcasting) clones. It seems to me that the game mechanics and your character's skills should matter more than your manual dexterity.