I used Backup Exec for many years and never had any complaints about it. It was tricky to get the tape and library drivers right (don't use the manufacturer's ones, use Backup Exec's) but once I got everything humming it worked great. I set up daily, weekly, monthly, and manual backups and managed tape rotations. I kept a set of onsite disk backups so I could restore files deleted in error quickly, and the software would automatically overwrite the oldest ones with no oversight. I spent very little time administering it, and restored countless files as well as one entire server no sweat.
Now we're forced to use Networker. I'm not impressed so far, stuff that was intuitive before now requires me to look up how to do it. I've also run into a bug where it appears to be running a restore but in reality will never complete. No error message.