I'm going to go out on a limb here and say that comparisons to the Holocaust and world wars are in fact quite appropriate when discussing the magnitude of what Microsoft did to the history of computing, and by extension to human history overall.
The reason for this is simple. The effect of the Microsoft monopoly lasted so long and was so stultifying that it meant we will never know what a different word processor might be like. We will never know if spreadsheets or email might be more usable or efficient. We will never know (at least not in our lifetime) what an operating system or software might be like that doesn't use the conventions laid down by a company that had no incentive to make anything better, no need to design anything more than barely adequate, or to listen to its customers. Yet all these things are of fundamental importance to our lives - far, far too important to have suffered under a brutal, money-grubbing monopoly.
Despite (very) small innovations, Apple was not and is not a counter-balance because they were forced to ape the conventions that the Microsoft juggernaut had laid down with it's 95% market share. Jobs knew as well as anyone that it would be suicide to create anything that the market place was not already at least partially familiar with.
In the final analysis, the Microsoft era was a massive failure of free market capitalism that left us all driving Trabants while thinking they were the best that we could have. The blame lies of course with politicians and industry regulators who had no clue what an immense influence personal computing would have on society until it was too late. But it is too late. The die has been cast for personal computing for generations to come, and that is an utter and maddening tragedy for all of us.
The issue is of course far bigger than just one man, but holy mother of god do I hate what Bill Gates did to all of us.