I was working for a small aerospace startup. We had a project to test molecular beam epitaxy on a project to fly on the shuttle. I built most of their PC,s, ran the network, provided support, etc. Our platform, at the time, was the 486 processor. This new-fangled processor the 586, came out, and the lil PhD that did the orbital dynamics of the project just had to have one. Having been the victim of several arrows in the back, I had a rather adamant aversion to using version 1.0 of anything. I argued, and won, we would not use the 586 yet.
Welllllll, they snuck one past me as a piece of "test" equipment.
The project was placed on the shuttle, and when it came time to fly, it was lifted from the payload bay by the arm, and activated. It could not lock guidance. It would only wobble. Long story short, after several attempts, re-uploading flight software, and a second flight on the shuttle. The project was scrapped.
Several weeks after the second flight, I made sure that the articles about the Intel 586 floating point error were in everyones' in-box. About two years later, the company went under. Doubt it was because of the problem with the 586.... it was more because the company was a threat to the traditional way NASA does business.