Comment Re: Good luck... (Score 1) 301
Let's suppose this works as advertised, and so, almost inevitably, house mice become extinct in Eurasia as well. Before reintroducing them you'd have to wait until they are *completely* extinct there (including on islands and in other remote places), which might take decades during which the lack of house mice might cause serious damage to European ecosystems.
The species normally has a very large population, hence genetic diversity. It's not clear what will happen if you introduce a serious evolutional bottleneck. It's not clear if New Zealand (or any other part of the New World where mice now live) is a precedent for longterm survival of the species after such a bottleneck, as they probably had centuries of genetic diversity arriving regularly on board European ships.
Female house mice are easy to identify. But you also need unaffected male house mice without the engineered gene - and enough of them to get a sufficient degree of variation on the Y chromosome. You need enough unaffected mice to have the genetic diversity required for long-term survival in the mice's original ecosystems, where their niche has been taken over by other species. You need sufficient funding for this without being able to say how many, precisely, you need. You will have to fight against short-sighted agricultural ministers in much the same way that other interests are currently holding up the reintroduction of other species - and effective action to save the planet from climate change.
You'd also need to make sure that nobody releases their pet mouse with the gene after you have started reintroducing mice.