I'd go out on a limb and say it's not clear we need malaria-proof anything.
Spraying -- since the end of the civil war in Mozambique -- and distributing treated mosquito nets has greatly reduced Malaria in Mozambique and the lowveld regions of South Africa. Malaria was eliminated in Europe and the US without malaria-proof mosquitoes. (Remember that nasty DDT? It was intended solely for spraying the inside walls of houses in the south. Farmers saw how well it worked and started spraying it on their crops, and the rest is history.)