People often say that the control key combinations are difficult in Emacs, but
this is only so if 1) you don't touch-type and 2) your keyboard is older than 20 years.
On a modern (=post 90s) keyboard, there are two control keys and two alt keys,
one for each hand.
Here's how you should type a typical Emacs chordal command: use both hands.
For example, M-x is typed by pressing the x with the left hand, and the ALT with the right hand. This is touch typing 101. (Similarly, you would type a capital letter by pressing the letter with the nearest hand, and pressing shift with the other hand.)
You can still reprogram your keyboard, and you can change the key combinations
in your .emacs if you prefer something else, but if you think about it a little, all the commands you're likely to need can be typed comfortably if you use both hands simultaneously.