pirateninja writes "Dr. Gord Cormack decided to find and prove what the best spam filter is. In his study he looked at the major spam filters (DSPAM, SpamAssassin, etc.) along with those submitted by various academics. The results are quite surprising, with a previously unheard-of spam filter, which uses ideas from various compression algorithms, performing the best overall. He recently presented the results and methodology used in a presentation titled 'Spam Filters, Do they Work? and Can you prove it?'"
Note that this is a video of his presentation.