Best Bioinformatics Software for Enterprise

Emedgene streamlines tertiary analyses for germline research and rare disease genomics. Emedgene was designed to speed up the time and certainty of user-defined variant interpretations, prioritizations, curations, and research reports. Automate your tertiary analyses with explainable AI and automation that supports genomes, exomes and virtual panels. Unify your NGS instruments and your IT systems in order to simplify and secure the entire workflow. With the latest knowledge graph options, curation abilities, and a team to support you, you can confidently keep up with evolving science, technologies, and demand. Automated workflows and explainable AI (XAI), which can be used to increase throughput without adding more staff, are a great way to do this. Implement a high-throughput WGS,WES, virtual panel or targeted panel workflow integrated into your lab's ecosystem.

Store, archive, and manage multi-omic data sets. Illumina Connected Analytics provides a secure platform for genomic data to operationalize informatics, and drive scientific insight. CWL and Nextflow allow you to easily import, build and edit workflows. Leverage DRAGEN bioinformatics pipelines. Organize your data in a safe workspace and share it with the world in a compliant way. Our platform allows you to keep your data in the cloud. Visualize and interpret data using a flexible analysis tool, such as JupyterLab Notebooks. Data warehouses allow you to aggregate, query and analyze sample data and population data. Scale analysis operations through the creation, validation, automation, and deployment of informatics pipelines. Reduce the time needed to analyze genomic data when quick results are a key factor. Enable comprehensive profiling for the identification of novel drug targets and biomarkers of drug response. Data can be transferred seamlessly from Illumina sequencing platforms.

Illumina DRAGEN Secondary Analysis is a comprehensive and accurate analysis of next-generation sequence data. Machine learning and graph reference genome drive unprecedented accuracy. Ultra-efficient workflow. Can process a whole 34x human genome in under 30 minutes using DRAGEN server version 4. Reduces FASTQ files up to 5x, resulting in an ultra-efficient workflow. Analyzes data from next-generation sequencing (NGS), including whole genomes, transcriptomes, methylomes and exomes. Available on the platform of your choice and scalable according to needs. DRAGEN analysis is the most accurate for germline and somatic mutation calling, as demonstrated by precisionFDA's industry challenges. DRAGEN analysis allows labs of any size and discipline to do more with genomic data. DRAGEN analysis is based on highly reconfigurable FPGA technology to provide hardware-accelerated implementations for genomic analysis algorithms.

Data management and simplified Bioinformatics are ideal for labs that are just getting started or for those who want to scale up their next-generation sequencing operations quickly. BaseSpace Sequence hub is an integral part of the BaseSpace Suite and is a direct extension to your Illumina instruments. BaseSpace Sequence hub allows you to manage your data with ease using a set of curated analysis apps. BaseSpace Sequence hub is powered by Amazon Web Services. Provides a secure environment. You can set up runs and monitor the quality of instrument runs. By converting sequence data into a standard format, and streaming it directly to the cloud, this tool promotes efficiency. Access to computing resources is available without the need for capital expenditures. Access to a variety of genomic analysis apps, whether provided by you, Illumina or third parties, increases organizational productivity.

Microsoft's experience and scale in managing exabyte-scale workloads can be used to reduce the need for you to manage your own data center. Microsoft Genomics on Azure gives you the performance and scalability that comes with a supercomputing facility of the highest caliber, all on demand. Take advantage of an MPI backend network that has a latency of under three microseconds, and a non-blocking throughput of 32 gigabits per seconds (Gbps). This backend network features remote direct memory access, which allows parallel applications to scale up to thousands of cores. Azure offers high memory and HPC class CPUs to help get results quickly. Scale up or down according to your needs and only pay for what you actually use. Azure's worldwide network of data centers can help you meet your compliance needs and address data sovereignty issues. Easy integration into your existing pipeline code with a REST API and simple Python client.

Software for fast, simple, and repeatable analysis of variants in gene panels, whole genomes, and exomes. VarSeq provides an intuitive and integrated software solution for tertiary analyses. VarSeq allows you to automate workflows and analyze variations for gene panels, whole genomes, and exomes. Our software makes it easier than ever to understand genomic data. VarSeq is a powerful software that provides a powerful filtering engine and annotation engine for sifting through large variant data. You can narrow down your list of variants quickly by using a series of filters. You can save the filters you have created after you have determined the parameters that are most effective for your analysis. This allows you to easily apply the same analysis on another dataset. VarSeq is ideal for high-throughput environments because the same automated workflow can apply to each batch of samples. Real-time filtering allows you to quickly prototype and fine-tune analysis workflows.

VSClinical allows the clinical interpretation based on ACMG & AMP Guidelines. The VSClinical workflow is guided by the American College of Medical Genetics guidelines for identifying and classifying causal variants in inherited disease risk, predisposition to cancer, and diagnosis of rare diseases. The ACMG/AMP Joint Guidelines for Variant Interpretation provide a set criteria to score variants, and place them in one of five classification tiers. The guidelines require a deep dive into the annotations and genomic context of each variant, as well as existing clinical assertions. VSClinical offers a customized workflow to score each relevant criteria, while also providing bioinformatics, literature and evidence gathered from clinical knowledgebases. VSClinical was designed to help variant scientists process variants efficiently.

GenomeStudio Software allows you to visualize and analyze data from Illumina array platforms. This powerful tool supports genotyping analysis of microarray datasets. Performance-optimized tools and a user-friendly graphical interface enable you to convert data into meaningful results quickly and easily. Analyze SNP/CNV data across 5,000,000 probes and markers. Detect outliers in sample data. Analyze differentially expressed genes across multiple genomes. Profile miRNA expression. Combine microRNA and mRNA data into one project. Single-base resolution detection of cytosine methylation. Identify methylation signatures throughout the entire genome. Illumina's goal is to use innovative technologies to analyze genetic variation and function. This will allow us to do studies that were impossible just a few short years ago. We believe it is vital to provide innovative, flexible, and scalable solutions that meet the needs of customers.

Polly allows you to harness the power of biomedical information. The Polly Platform allows you to scale batch jobs, workflows and visualization applications. Polly supports resource pooling, optimizes resource allocation based upon your usage requirements, and makes use of spot instances when possible. This results in optimization, efficiency, quicker response time, and lower costs for resources. Access a dashboard that allows you to monitor and track resource usage and costs in real-time. This will allow you to reduce overheads when resource management is done by your IT team. Polly's infrastructure is built around version control. Polly uses a combination dockers and interactive notebooks to ensure version control for your analyses and workflows. We have created a mechanism that allows data, code, and the environment to co-exist. This, along with cloud data storage and the ability for users to share projects, ensures reproducibility in every analysis.

A robust platform for automatic variant prioritization and clinical interpretation, as well as report generation, is essential to ensure efficient reporting of NGS-based clinical trials. Strand Omics, a cloud-based platform that is HIPAA-compliant and fast, drives our clinical diagnostics practice. It has been refined over 4 years with over 10,000 clinical reports and multiple peer reviewed publications. Strand Omics is a combination of bioinformatics algorithms and curated databases, visualization interfaces, and reporting capabilities. It offers specialized workflows that can be used for rare inherited disorders and somatic tumor profiling tests. The platform has over 10,000 variants curated to oncogenicity, 100 genes that are curated for druggability across multiple types of cancer, and 500 drugs that have been curated for evidence.

Eidogen-Sertanty’s Target Informatics platform (TIP), is the first global structural informatics system. It enables researchers to examine the druggable genome from an structural perspective. TIP increases the rapidly expanding body experimental protein structure information and transforms structure based drug discovery from an inefficient, data-scarce discipline to a high-throughput science with rich data. TIP is a tool that bridges the knowledge gap between bioinformatics (bioinformatics) and cheminformatics. It provides drug discovery researchers with a knowledge bank of information that is both unique and highly complementary to existing bio- and cheminformatics platform information. TIP's seamless integration between structural data management technology and unique target-to-lead analysis capabilities enhances every stage of the discovery pipeline.

Stop messing around with broken informatics tools and cloud infrastructure. Get started today on uncovering biological insights. Scientists are often limited by the fragmentation of tools across biology and bioinformatics teams. To help teams accelerate their R&D, we created a harmonized platform for bioinformatics between the cloud and the wet lab. Import raw data from your cloud service provider, your team's instruments, or your cloud. Create and deploy custom bioinformatics workflows using any language. Stop wasting time tinkering with your infrastructure. You can easily run any workflow and keep track of every analysis. Interactive visualizations of NGS data ready-to-go with point-and click plots Latch integrates with your AWS S3. You can access hundreds of terabytes in organic filesystems you are familiar with. Create bioinformatics workflows, and dynamically create no-code interfaces with Python with tunable storage and compute.

Swiss-PdbViewer, also known as DeepView, is an application that allows you to analyze multiple proteins simultaneously. To compare active sites and other parts, the proteins can be superimposed. The intuitive interface and graphic make it easy to find information about amino acid mutations, Hbonds, angles and distances between atoms. Nicolas Guex has been developing Swiss-PdbViewer (aka DeepView), since 1994. Swiss-PdbViewer was originally tightly connected to SWISS-MODEL (an automated homology modeling server) that was developed at the Structural Bioinformatics Group of the Biozentrum in Basel. The SWISS-MODEL interface has evolved to the point that advanced modeling can now be done directly. It is no longer possible to maintain a direct interface with SwissPdbViewer.

Avogadro, an advanced molecule editor/visualizer, is designed for cross-platform usage in computational chemistry and molecular modeling. It provides high-quality rendering and a powerful plugin structure. Avogadro, a free and open-source molecular editor/visualization tool, is available for Mac, Windows, and Linux. It can be used in computational chemistry and molecular modeling as well as materials science and other related areas. It provides flexible, high-quality rendering and a powerful plugin structure.

IDBS Polar is the first BioPharma lifecycle management (BPLM) platform in the world. It eliminates repetitive manual tasks and allows you to execute your processes efficiently while curating data. This will allow you to accelerate the time to market, by tackling the most challenging challenges of process design, optimization scale-up and technology transfer. Interactive data analytics applications such as bioreactor comparision designed specifically for biopharmaceutical development scientists. IDBS Polar is an integrated platform that manages drug progress in contexts such as workflow, integration and insight. Workflows designed for the BioPharma lifecycle, with process-aware design, planning, and execution. Integrations that give meaning to your data. Rapid integration into your development environment, enabling automation, and curating a data backbone based on processes.

The XetaBase platform is unique in that it simplifies tertiary analyses by aggregating, indexing and enriching secondary genome data. This allows for a continual reinterpretation of the data to unlock clinical and research insights. XetaBase enables the rapid management of genomic data and its cost-effective use in the laboratory and clinic. XetaBase is a genomic-scale platform. The greater the volume and the complexity, the better the insights and outcomes. XetaBase, a genomic-native platform, is built on the OpenCB open-source software platform. It meets the demands of genomic medicine for speed, scale, and reinterpretation. Zetta Genomics provides genomic data management that is fit for the precision-medicine age. XetaBase offers a novel solution for the challenges of genomic information. It replaces outdated flat file approaches and brings meaningful and actionable genome data to the lab and clinic. XetaBase allows for continual reinterpretation and scales seamlessly as databases expand to include genome sequences.

g.nome is a cloud-native, workflow-optimized platform that provides streamlined, scalable and interoperable workflows to perform next-generation sequencing analyses. g.nome offers a low-code/no code pipeline build. Using pre-built toolkits and workflows from a curated collection, g.nome gives researchers the power to import custom code and handle large datasets reliably. With g.nome you can remove long-standing barriers related to workflow language, visibility of process flow, and quality control. All that's left is streamlined, interoperable, and scalable genomic workflows. This allows research teams to focus on what they do best, which is the science.

Metabolon offers the largest Level 1 library available in the metabolomics field. Over 5,400 entries are contained in our proprietary library, which has been built over 20 years. The majority of entries are Level 1, accounting for approximately 85% of our library (4,600 entries). However, some are level 2 (approximately 15 % of the entries), due to a lack commercial standards to qualify for Level 1. Metabolon's unmatched library breadth, industry-leading annotation confidence level and unmatched library depth enable us to provide our clients with accurate, highly actionable insight for their scientific or clinical inquiries. Metabolomics is applicable to a wide variety of research, including soil health, food nutrition, preclinical research and clinical trials. Whether you are looking for trends within a group, or modifying an individual's treatment plan, metabolomics will help you find the answers you need.

Accuracy, speed, confidence. Introduce generative AI in commercial biopharma. Simplify the laborious process of collecting, organizing and inspecting vast quantities of complex data. You can always rely on 100% accuracy to get the insights you need. You'll never again lose track of your workflows with our AI-powered data verification and manipulation platform. All in one place, you can gather, refine and check all your data. Search public and private databases based on key drug characteristics. Segment drugs and clinical trials based on detailed patient profiles. You can extract the data in plain English. Link your answers to their original source. Spend your time and effort on synthesising high-quality outputs rather than sifting through data. Our LLMs allow researchers to scan assets 4.8x faster by hand. We index more than 38M scientific publications and abstracts from conferences, clinical trials, and other sources. All the data that you need, at the time you need it.

Our global data-sharing networks generate clinically actionable insights to improve patient outcomes globally. SOPHiA GENETICS is on a mission to build the future in AI-assisted medical care. We are integrating multimodal data from healthcare-omics, unlocking existing data silos and developing machine learning models in order to produce actionable insight that can eventually support healthcare professionals improve patient outcomes. The new interface, features, and cutting edge capabilities will accelerate precision medicine workflows and bring us closer to democratizing the data-driven medicine.

Combinatorial barcoding technology removes the limitations and frustrations associated with yesterday's single cell approach. It eliminates the need for a specialized instrument and allows you to make new discoveries. Unleash the power of a single cellular. In a single experiment you can profile up to 1,000,000 cells or nuclei, allowing for unprecedented scientific progress. Evercode's combinatorial barcoding technology is superior to droplet-based approaches. You can now expand the size of your experiment without the restrictions of the past. Get better data quality. All without the need to use finicky hardware which is already outdated. You can perform single-cell experiments using a pipette, common laboratory equipment and a pipette. Split-pool combinatorial barscoding allows for scalable single cells, without the need for a custom instrument. Scalable single-cell sequence without the instrument. Each kit includes end-to-end reagents for solution and intuitive analysis software.

Loupe Browser is an intuitive visualization software that allows you to explore and analyze 10x Genomics Chromium or Visium data. LoupeR can convert Seurat objects to Loupe Browser files. The Loupe Browser interface's navigation and interactive features are based on a dataset of lung squamous-cell carcinoma. The workspace is centered on the view panel, where single points representing barcodes of cells are shown in different projections. Each point represents a barcode. The vast majority of them correspond to a cell. The default projection, created by the Cell Ranger pipeline, is the tSNE plot. Other projections are also available. You can move the plot by dragging the mouse over cells. Zoom in and out using the mouse wheel or trackpad. Cluster labels will appear as you move the mouse over the plot. This is useful for data with a large number of precomputed groups.

Choose two custom cell groups and compare their top differentially-expressed genes. Use millions of cells in the integrated CZ CELLxGENE Corpus for powerful analyses. Use an interactive, no-code interface to perform interactive analyses of a dataset. Explore how spatial, environmental and genetic factors influence gene expression patterns. Use published datasets to understand them or as a starting point for identifying new cell subtypes and states. Census allows you to access any custom slice of standard cell data from CZ CELLxGENE in R or Python. Explore an interactive encyclopedia that contains 700+ cell types, detailed definitions, markers genes, lineage and relevant datasets. Browse and download 1,000+ datasets and hundreds of standardized data sets that characterize the functionality of healthy human and mouse tissues.

We help healthcare systems reduce their burden by providing automated analysis, diagnosis and treatment solutions to healthcare professionals and patients around the world. Congenica was founded by pioneering work done at the Wellcome Sanger Institute in the UK and the NHS. Our products combine the latest technology, automation and AI to create a platform that is uniquely differentiating. This platform can be used in any area of human disease, where genomic data is critical to unlocking actionable insight. We are a digital healthcare company that provides software and solutions to analyze and interpret genomic data at large scale. Full automation using powerful APIs and ML, to reduce the burden of specialist staff, increase case throughput, speed up decision-making and streamline reporting. Platform for accurate, certified, and secure clinical decision support with the highest level of confidence in clinical outcome.

Alissa Interpret provides a universal software solution for the interpretation of genomic data in clinical decision support. Alissa Interpret is a platform that can be used for CGH or NGS tertiary analyses. It will increase your productivity, reduce turnaround time and maintain regulatory compliance. Alissa interpret, Agilent's SureSelect NGS reagents and intuitive Alissa Reporter for secondary NGS analysis, Magnis walkaway automated, and TapeStation QC will help you achieve complete operational efficiency. You can access external and internal variant knowledgebases. Automated variant analysis solution accelerates CGH/NGS tertiary analyses. SNVs and InDels are all handled by the same platform. CNVs, LOHs, fusions, CNVs and InDels can also be analyzed. Integrate with your LIMS to eliminate bottlenecks in genomic data analysis. Connect with peers to share knowledge and improve diagnostic yield.