Medicine

Scientists Finally Unlock the Recipe For Magic Mushrooms (gizmodo.com) 132

An anonymous reader writes: Aside from being a schedule 1 drug, scientists haven't fully understood the chemistry behind how mushrooms produce the chemical psilocybin -- until now. A new study may finally lay the groundwork for a medical-grade psilocybin patients can take. Gizmodo reports: "Living things make molecules through a series of chemical reactions, similar to how car makers produce cars on assembly lines. Enzymes act as the workers/robots, speeding up the reactions by helping put the pieces together. Actually making psilocybin requires mapping the biological factory. A 1968 paper (obviously it was in 1968) offered a proposed order of events leading to a finished psilocybin molecule, by adding radioactive elements and watching what happened to them on the assembly line. The researchers thought that maybe tryptophan, the amino acid everyone wrongly says makes you sleepy, was the first piece, which then went through four successive steps to become the finished product. The new study shows that the 1968 paper got the order wrong, and introduces the responsible genes and enzymes, the workers that do the specific task to get the final product. This time around, mapping the factory required sequencing the genomes of two magic mushroom species, Psilocybe cubensis and Psilocybe cyanescens. Then, the researchers found exactly which genes produce the required enzymes and spliced them into E. coli bacteria. Using those enzymes, they were able to rebuild the factory and create their own psilocybin." The study has been published in the German journal Angewandte Chemie.
Intel

Intel Officially Reveals Post-8th Generation Core Architecture Code Name: Ice Lake, Built On 10nm+ (anandtech.com) 95

Intel has confirmed the existence of a new processor family called Ice Lake that will be made on Intel's 10nm+ process. The company published basic information on the Ice Lake architecture on their codename decoder. AnandTech reports: This is an unexpected development as the company has yet to formally detail (let alone launch) the first 10nm Core architecture -- Cannon Lake -- and it's rare these days for Intel to talk more than a generation ahead in CPU architectures. Equally as interesting is the fact that Intel is calling Ice Lake the successor to their upcoming 8th generation Coffee Lake processors, which codename bingo aside, throws some confusion on where the 14nm Coffee Lake and 10nm Cannon Lake will eventually stand. As a refresher, the last few generations of Core have been Sandy Bridge, Ivy Bridge, Broadwell, Haswell, Skylake, with Kaby Lake being the latest and was recently released at the top of the year. Kaby Lake is Intel's third Core product produced using a 14nm lithography process, specifically the second-generation '14 PLUS' (or 14+) version of Intel's 14nm process.

Working purely on lithographic nomenclature, Intel has three processes on 14nm: 14, 14+, and 14++. As shown to everyone at Intel's Technology Manufacturing Day a couple of months ago, these will be followed by a trio of 10nm processes: 10nm, 10nm+ (10+), and 10++. On the desktop, Core processors will go from 14 to 14+ to 14++, such that we move from Skylake to Kaby Lake to Coffee Lake. On the Laptop side, this goes from 14 to 14+ to 14++/10, such that we move from Skylake to Kaby Lake to Coffee Lake like the desktops, but also that at some time during the Coffee Lake generation, Cannon Lake will also be launched for laptops. The next node for both after this is 10+, which will be helmed by the Ice Lake architecture.

Patents

Toyota Patents Cloaking Device To Make Car Pillars Appear Transparent (thedrive.com) 105

Toyota has patented a cloaking device that aims to make big, chunky car pillars transparent. The "apparatuses and methods for making an object appear transparent" which Toyota just patented uses cleverly placed mirrors to bend light around an object making it visible from the other side. The Drive reports: So you're not really seeing through the pillars, you're seeing around them. This is a much cheaper option than adding more cameras and screens all over the place and much more realistic than Harry Potter's invisibility cloak. The patent was filed with the U.S. patent office by Toyota North America, so if Toyota does go forward with this technology, we can probably expect to see it in cars in the U.S.
Businesses

Amazon Adds 'Instant Pickup Points' In US Brick-And-Mortar Push (reuters.com) 59

An anonymous reader quotes a report from Reuters: Amazon is rolling out U.S. pickup points where shoppers can retrieve items immediately after ordering them, shortening delivery times from hours to minutes in its latest move into brick-and-mortar retail. The world's largest online retailer has launched 'Instant Pickup' points around five college campuses, such as the University of California at Berkeley, it said on Tuesday. Amazon has plans to add the program to more sites by the end of the year. Shoppers on Amazon's mobile app can select from several hundred fast-selling items at each location, from snacks and drinks to phone chargers. Amazon employees in a back room then load orders into lockers within two minutes, and customers receive bar codes to access them.
Software

App Developers Should Charge More If They Want People To Buy Subscriptions, Suggests Report (theverge.com) 50

A new report from Liftoff, a Silicon Valley-based mobile app marketing and retargeting firm, says that subscription-based apps may do better if developers charge a higher price for services, rather than setting prices too low to lure users in initially. The Verge reports: The Liftoff report, which analyzed data gathered between June 2016 and June 2017, categorized app subscriptions into low-cost monthly subs ($0.99 to $7), medium ($7 to $20), and high-cost subs ($20 to $50), while also factoring the cost of acquisition per customer. The company found that apps in the medium price range had the highest conversion rate -- 7.16 percent -- and the lowest cost to acquire a subscriber, at just over $106 dollars. This was five times higher than the rate of people who subscribed to apps when the apps were in the low-cost category. This may partly be because streaming media apps, like Netflix and Spotify, have already conditioned people to pay around $10 a month for services. But it also might be attributable to the sunk cost fallacy, Liftoff says: the "cognitive bias people have that makes them stay the course because they have already spent time or resources on it." The report also examines apps that fulfill "need states," like dating apps or cloud services. These have the potential to offer services that customers are willing to pay for, again and again. But, according to Liftoff, utility apps have a much higher install-to-subscriber rate compared to dating apps. Blame those who eventually find love?
Communications

Neo-Nazi Site The Daily Stormer Moves To Dark Web After Shutdown (vice.com) 337

After being shutdown by Google and GoDaddy, prominent neo-Nazi website The Daily Stormer has moved their site to the dark web. "The new site is now only available through the Tor network, which allows users to set up their own domains," reports VICE News. "The original site, Dailystormer.com, is now fully offline." From the report: The homepage, as of Tuesday morning, contained articles that make light of the car ramming attack that claimed the life of 32-year-old Heather Heyer; admonish the "Jew media;" liberally employ various racial epithets; and, in a less offensive post, provided an update on which characters are available on Pokemon Go. In a statement, the site's founder promised to bring his site back online. "The Daily Stormer will be live in internet prison with drug dealers, terrorists and perverts, which is where we've been exiled to, for all time," Andrew Anglin said in a statement sent to VICE News. "We should have a real domain online within 24 hours. If it gets shut down again, people will know we are on the black web."
Medicine

Plants 'Hijacked' To Make Polio Vaccine (bbc.com) 59

Plants have been "hijacked" to make polio vaccine in a breakthrough with the potential to transform vaccine manufacture, say scientists. From a report: The team at the John Innes Centre, in Norfolk, says the process is cheap, easy and quick. As well as helping eliminate polio, the scientists believe their approach could help the world react to unexpected threats such as Zika virus or Ebola. Experts said the achievement was both impressive and important. The vaccine is an "authentic mimic" of poliovirus called a virus-like particle. Outwardly it looks almost identical to poliovirus but -- like the difference between a mannequin and person -- it is empty on the inside. It has all the features needed to train the immune system, but none of the weapons to cause an infection.
Communications

Guam Radio Stations Accidentally Conduct Emergency Alert Amid North Korea Threat (theguardian.com) 50

the_webmaestro writes: A couple of radio stations in Guam conducted an unscheduled test of the Emergency Alert Broadcast System, sending some residents -- already on edge due to the back and forth between the North Korean regime and the tweets made by the President of the United States -- into a panic. From the Guam Homeland Security/Office of Civil Defense Facebook page: "The Offices of Guam Homeland Security and Civil Defense (GHS/OCD), in conjunction with the Mariana Regional Fusion Center (MRFC), our federal and military partners, continue to monitor the recent events surrounding North Korea and their threatening actions. Residents and visitors may have noticed at 12:25 a.m., an unscheduled test of the Emergency Alert Broadcast System (EAS) was triggered from KTWG/KSTO AM. The message read: 'A BROADCAST STATION OR CABLE SYSTEM HAS ISSUED A CIVIL DANGER WARNING FOR THE FOLLOWING COUNTIES/AREAS: Guam, Guam; AT 12:25 AM ON AUG 15, 2017 EFFECTIVE UNTIL 12:40 AM. MESSAGE FROM KTWGKSTO.' The unauthorized test was NOT connected to any emergency, threat or warning. GHS/OCD has worked with KSTO to ensure the human error will not occur again. There is no scheduled test of the EAS or All Hazards Alert Warning System sirens today."

In addition, the Guam Power Authority (GPA) reported there were two scheduled outages, for emergency interruption of power, at 2:30 p.m. and 7 p.m., August 14: "Unrelated to the EAS unauthorized test, the Guam Power Authority (GPA) reported there were two scheduled outages, for emergency interruption of power, at 2:30 p.m. and 7 p.m., August 14 for customers located in Talofofo located along along Rte.17, Chalan J. Kindo, Vicente Borja Dr., Felix Dydasco St., Henry Simpson area to bus shelter by Bishop Street and other customers in these locations."

Businesses

Amazon Is Seeking $16 Billion Bond Sale For Whole Foods (bloomberg.com) 46

An anonymous reader quotes a report from Bloomberg: Amazon is turning to the debt markets to fund the $13.7 billion acquisition of Whole Foods and power Jeff Bezos's planned conquest of the supermarket business. The world's largest online retailer is selling $16 billion of unsecured bonds in as many as seven parts, according to a person with knowledge of the matter. In a sign of market interest, the longest portion of the offering, a 40-year security may yield 1.45 percentage points above Treasuries, down from initial talk of 1.6 percentage points to 1.65 percentage points, said the person, who asked not to be identified as the deal is private. The sale marks the first bond-market foray since 2014 for Amazon and will support the purchase of the organic-food chain, according to a company statement. The partnership, which rattled the grocery world when announced in June, is expected to reduce prices at Whole Foods, an iconic yet struggling high-end grocery trying to lure more low- and middle-income shoppers. The deal could intensify a price war in an industry beset by razor-thin margins and persistent deflation.
The Internet

Cloudflare is the One Tech Company Still Sticking By Neo-Nazi Websites (qz.com) 549

An anonymous reader shares a report: One company is sticking by The Daily Stormer and other far-right websites: the cloud security and performance service Cloudflare. Cloudflare acts as a shield between websites and the outside world, protecting them from hackers and preserving the anonymity of the sites' owners. But Cloudflare is not a hosting service: It does not store website content on its servers. And that fact, as far as the company is concerned, exempts it from judgment over who its clients are -- even if those clients are literally Nazis. In a statement Cloudflare sent to Quartz and other publications yesterday, the company refused to explicitly say it will continue to do business with sites like The Daily Stormer, but pointed out that the content would exist regardless of what Cloudflare does or doesn't do. "Cloudflare is aware of the concerns that have been raised over some sites that have used our network. We find the content on some of these sites repugnant. While our policy is to not comment on any user specifically, we are cooperating with law enforcement in any investigation. Cloudflare is not the host of any website. Cloudflare is a network that provides performance and security services to more than 10% of all Internet requests. Cloudflare terminating any user would not remove their content from the Internet, it would simply make a site slower and more vulnerable to attack."
UPDATE: The Daily Stormer now says Cloudflare has decided to drop their site after all.
Businesses

'Biggest Data Center' To Be Built in Arctic (bbc.com) 41

A small town in the remote north of the Arctic Circle is set to be home to the world's largest data center. From a report: The firm behind the project, Kolos, says the chilled air and abundant hydropower available locally would help it keep its energy costs down. The area, however, suffers the country's highest rate of sick leave from work, which may be related to its past as a mining community. The US-Norwegian company says it has already raised "several million dollars" for the project from Norwegian private investors. However, it is still working with a US investment bank to secure the remaining necessary funds.
Businesses

No Cash For Hate, Say Mainstream Crowdfunding Firms (reuters.com) 396

An anonymous reader shares a report: Online fund-raising sites are turning their backs on activists looking to offer financial support for James Fields, the man accused of driving his car into counter-protesters at a white-nationalist rally in Charlottesville, Virginia on Saturday. GoFundMe, Kickstarter and other mainstream crowdfunding firms have policies that prohibit hate speech or abuse, the latest example of technology firms making it harder for far-right groups to organize online. Fields is accused of killing one woman and injuring 19 others on Saturday after the rally in Charlottesville turned violent. Supporters of Fields, who was denied bail at a court hearing in Virginia on Monday, have turned to the internet to raise money for his legal defense. GoFundMe, one of the two leading crowdfunding firms, said on Monday it has removed multiple fundraising campaigns for Fields, because the company prohibits the promotion of hate speech and violence.
Communications

Tech Companies Urge Supreme Court To Boost Cellphone Privacy (reuters.com) 29

More than a dozen high technology companies and the biggest wireless operator in the United States, Verizon, have called on the U.S. Supreme Court to make it harder for government officials to access individuals' sensitive cellphone data. From a report: The companies filed a 44-page brief with the court on Monday night in a high-profile dispute over whether police should have to get a warrant before obtaining data that could reveal a cellphone user's whereabouts. Signed by some of Silicon Valley's biggest names, including Apple, Facebook, Twitter, Snap and Alphabet's Google, the brief said that as individuals' data is increasingly collected through digital devices, greater privacy protections are needed under the law. "That users rely on technology companies to process their data for limited purposes does not mean that they expect their intimate data to be monitored by the government without a warrant," the brief said.
Science

Feeling Bad About Feeling Bad Can Make You Feel Worse (berkeley.edu) 102

An anonymous reader writes: Pressure to feel upbeat can make you feel downbeat, while embracing your darker moods can actually make you feel better in the long run, according to new UC Berkeley research. "We found that people who habitually accept their negative emotions experience fewer negative emotions, which adds up to better psychological health," said study senior author Iris Mauss, an associate professor of psychology at UC Berkeley. At this point, researchers can only speculate on why accepting your joyless emotions can defuse them, like dark clouds passing swiftly in front of the sun and out of sight. "Maybe if you have an accepting attitude toward negative emotions, you're not giving them as much attention," Mauss said. "And perhaps, if you're constantly judging your emotions, the negativity can pile up."
NASA

NASA is Sending Bacteria Into the Sky on Balloons During the Eclipse (cnbc.com) 54

An anonymous reader shares a report: As the Moon blocks the Sun's light completely next week in a total solar eclipse, more than 50 high-altitude balloons in over 20 locations across the US will soar up to 100,000 feet in the sky. On board will be Raspberry Pi cameras, weather sensors, and modems to stream live eclipse footage. They'll also have metal tags coated with very hardy bacteria, because NASA wants to know whether they will survive on Mars. Every time we send a rover to the Red Planet, our own microorganisms latch on to them and hitch a ride across space. What happens to these bacteria once they're on Mars? Do they mutate? Do they die? Or can they continue living undisturbed, colonizing worlds other than our own? To answer these questions we need to run experiments here on Earth, and the eclipse on August 21st provides the perfect opportunity. The balloons are being sent up by teams of high school and college students from across the US as part of the Eclipse Ballooning Project, led by Angela Des Jardins of Montana State University. When Jim Greene, the director of planetary science at NASA, first heard that over 50 balloons were being flown to the stratosphere to live stream the eclipse, he couldn't believe his ears. "I said, oh my god, that's like being on Mars!" Greene tells The Verge. NASA couldn't pass on the opportunity.
Microsoft

We're Not Walking Away From Continuum, Says HP (theregister.co.uk) 44

An anonymous reader shares a report: While Windows roadmaps purportedly leaked to a blog last week appear to have a big hole in them where mobile should be, HP Inc tells us it has been assured by Redmond there are no plans to drop Continuum. HP is the sole major mobile vendor committed to the Windows Mobile Edition of Windows 10 and bet big on Continuum, the multimode "use-your-phone-as-a-PC" feature on which some of HP's ambitions rest. El Reg was impressed by HP's plans to build an ecosystem around the multi-mode capabilities of the HP Elite x3 phone, which doubles up as a PC replacement. (Or tries to.) Launching in over 50 markets, the ecosystem includes a streaming apps service HP Workplace to fill in the app gap, and even a "lap dock." HP pitched it at field workers and verticals. The only thing letting Inc-ers down was the quality of the software from Microsoft. Spring came and went without the expected improvements to Continuum. Unauthorised briefings last week suggest the Windows Mobile branch of Windows 10 is now an orphan.
Businesses

Netflix Co-Founder's Crazy Plan: Pay $10 a Month, Go to the Movies All You Want (bloomberg.com) 274

Mitch Lowe, a founder of Netflix, has a crazy idea. Through his new startup MoviePass, he wants to subsidize our film habit, letting us go to the theater once a day for about the price of a single ticket. From a report: Lowe, an early Netflix executive who now runs a startup called MoviePass, plans to drop the price of the company's movie ticket subscriptions on Tuesday to $9.95. The fee will let customers get in to one showing every day at any theater in the U.S. that accepts debit cards. MoviePass will pay theaters the full price of each ticket used by subscribers, excluding 3D or Imax screens. MoviePass could lose a lot of money subsidizing people's movie habits. So the company also raised cash on Tuesday by selling a majority stake to Helios and Matheson Analytics, a small, publicly traded data firm in New York. [...] Theater operators should certainly welcome any effort to increase sales. The top four cinema operators, led by AMC Entertainment, lost $1.3 billion in market value early this month after a disappointing summer.
Mozilla

64-bit Firefox is the New Default on 64-bit Windows (mozilla.org) 178

An anonymous reader shares a blog post: Users on 64-bit Windows who download Firefox will now get our 64-bit version by default. That means they'll install a more secure version of Firefox, one that also crashes a whole lot less. How much less? In our tests so far, 64-bit Firefox reduced crashes by 39% on machines with 4GB of RAM or more.
Intel

Intel CEO Exits President Trump's Manufacturing Council (axios.com) 263

Ina Fried, writing for Axios: Intel said Monday that CEO Brian Krzanich was leaving President Trump's American Manufacturing Council, the latest executive to distance himself from the president following the weekend's events in Virginia. In a blog post, Krzanich said that the decline in American manufacturing remains a serious issue, but said that "politics and political agendas have sidelined the important mission of rebuilding America's manufacturing base. I resigned to call attention to the serious harm our divided political climate is causing to critical issues, including the serious need to address the decline of American manufacturing," Krzanich said in a blog post. "Politics and political agendas have sidelined the important mission of rebuilding America's manufacturing base."
Businesses

Gates Makes Largest Donation Since 2000 With $4.6 Billion Pledge (bloomberg.com) 163

From a report: Bill Gates made his largest gift since the turn of the century, giving away Microsoft shares that accounted for 5 percent of his fortune, the world's biggest. The billionaire donated 64 million of the software maker's shares valued at $4.6 billion on June 6, according to a Securities & Exchange Commission filing released Monday. While the recipient of the gift wasn't specified, Gates has made the majority of his donations to the Bill & Melinda Gates Foundation, the charity he and his wife use to direct their philanthropic efforts. It's the largest gift of Microsoft shares that Gates has made since 2000. The 61-year-old gave away $16 billion worth of Microsoft shares in 1999 and $5.1 billion a year later, according to calculations by Bloomberg.
Government

Justice Department Demands 1.3 Million IP Addresses Related To Anti-Trump Website (theverge.com) 392

An anonymous reader quotes a report from The Verge: In a blog post today, online web hosting provider DreamHost disclosed that it has been involved in a months-long legal battle with the Justice Department over records on visitors to an anti-Trump website. The dispute focuses on a Justice Department demand for information on data related to disruptj20.org, which describes itself as a group of activists "building the framework needed for mass protests to shut down the inauguration of Donald Trump and planning widespread direct actions to make that happen." DreamHost is taking issue with a warrant issued by the department for "all files" related to the website, which DreamHost says would compel them to turn over electronic data like visitor logs. That would include IP addresses and other information that could be used to identify anyone who visited the site. "The request from the DOJ demands that DreamHost hand over 1.3 million visitor IP addresses -- in addition to contact information, email content, and photos of thousands of people -- in an effort to determine who simply visited the website," the company said in its blog post. The warrant, DreamHost argues, would also require it to hand over any communications that are even tangentially related to the website.

"In essence, the Search Warrant not only aims to identify the political dissidents of the current administration, but attempts to identify and understand what content each of these dissidents viewed on the website," the company said in a legal filing arguing against the warrant. A hearing on the situation is set for Friday in Washington, DC Superior Court.

Businesses

Snap Sold Fewer Than 42K Spectacles, Down 35% In Q2 (androidheadlines.com) 50

The hype surrounding Snap's Spectacles appears to be dwindling. Their sales have decreased by 35 percent in the second quarter of the year, with the company's latest consolidated financial report revealing that its "Other" revenue amounted to $5.4 million over the three-month period ending June 30. Android Headlines reports: With Spectacles being the company's only miscellaneous endeavor at this point in time and sporting a $130 price tag that has yet to see any discounts, it seems that the Venice, Los Angeles-based social media giant managed to only sell approximately 41,500 units of its first wearable in Q2 2017. During the first quarter of the year that also disappointed investors, Snap's "Other" business category recorded a revenue of $8.3 million, suggesting that the firm managed to sell around 64,000 units. The overall commercial performance of Spectacles may still improve during the current quarter as Snap just recently made the smart sunglasses available on Amazon, in addition to partnering with a number of physical retailers. Likewise, the Snapbot vending machines selling Spectacles only started appearing in Europe in June and are still popping up in a number of major cities on the Old Continent, which is another factor that could help improve the sales figures of Snap's camera-equipped pair of sunglasses. Regardless, the current state of affairs is unlikely to please investors, especially in light of the fact that Snap recently proclaimed itself to be "a camera company," noting how Snapchat is just one aspect of its product vision that's meant to incorporate a wide variety of photography-oriented hardware.
Businesses

Behind the Hype of 'Lab-Grown' Meat (gizmodo.com) 342

In an exclusive report via Gizmodo, Ryan F. Mandelbaum discusses the hype surrounding "lab-grown" meat: Some folks have big plans for your future. They want you -- a burger-eatin', chicken-finger-dippin' American -- to buy their burgers and nuggets grown from stem cells. One day, meat eaters and vegans might even share their hypothetical burger. That burger will be delicious, environmentally friendly, and be indistinguishable from a regular burger. And they assure you the meat will be real meat, just not ground from slaughtered animals. That future is on the minds of a cadre of Silicon Valley startup founders and at least one nonprofit in the world of cultured meat. Some are sure it will heal the environmental woes caused by American agriculture while protecting the welfare of farm animals. But these future foods' promises are hypothetical, with many claims based on a futurist optimism in line with Silicon Valley's startup culture. Cultured meat is still in its research and development phase and must overcome massive hurdles before hitting market. A consumer-ready product does not yet exist and its progress is heavily shrouded by intellectual property claims and sensationalist press. Today, cultured meat is a lot of hype and no consumer product.

"Much of what happens in the world of cultured meat is done for the sake of PR," Ben Wurgaft, an MIT-based post-doctoral researcher writing a book on cultured meat, told Gizmodo. Wurgaft finds it hard to believe many predictions about cultured meat's future, including the promise of an FDA-approved consumer product within a year. The truth is that only a few successful prototypes have yet been shown to the public, including a NASA-funded goldfish-based protein in the early 2000s, and a steak grown from frog cells in 2003 for an art exhibit. More have come recently: Mark Post unveiled a $330,000 cultured burger in 2013, startup Memphis Meats has produced cultured meatballs and poultry last and this year, and Hampton Creek plans to have a product reveal dinner by the end of the year.

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