I've done four road trips, about 8-10 weeks travel in total, stopping in at least 26 states. I've passed through or changed planes in a few more, but I don't count those. (In fairness, all except three of these states were when I was a child, and we only visited France and Ireland as a family.)
My US relatives (in their 40s) get two weeks leave a year, and tend to visit family.
The lack of Americans is most evident when backpacking. I was in Ecuador last year. You can divide the backpackers into students and non-students. There are some American students, but disproportionately few American non-students. (I'd expected to see more Americans on my first trip to South America, but it was little different to Asia.)