Since we are talking about the distant future, I was envisioning an automated craft that acted as vessel, womb, mother, and teacher. Craft would resume gestational development once it reached orbit. Wouldn't bother landing until the children had decanted, and had been taught sufficient survival skills. Then land, and let them apply their textbook learnin's as best as they can, do-or-die.
The problem with living crew is that-- as you mentioned-- they would evolve enough over time that they would lose interest in their original purpose. "Screw those embryonic proto-xenohumans, we xenohumans need to look out for 'Number One'."