Direct proof? Yes. I have had sections of my DNA sequenced by 3 different groups, using 3 different sequencers, including the whole of my mitochondrial DNA and various chromosomes from my nucleic DNA (Y is the easiest one to get sequenced multiple ways).
So far, differences detected: Zero.
So they are giving me valid SNPs everywhere I can double check.
Can I confirm SNPs I haven't had tested elsewhere? No, but sequencers only cost around $15 million, so if you could loan me the money, I can easily verify the rest. I would even be happy to verify results for anyone else who asked, at cost in electricity to run a batch divided by the number in that batch. I'll deal with the other costs.
Now, how fair is that? Total verification of the raw data results from any genome research group.
In fact, I don't care who supplies the cash. The FDA can, for all I care. I will then give you verification of any of these start-ups for slightly under the cost of the run itself, complete with statistical confidence limits because no test is 100% perfect.
I'm willing to sacrifice my time and effort on building an ultraclean room and buying the rest of the hardware and enzymes needed to take you from one anecdotal account to a full, absolutely independent (including of any existing lab) facility that can provide an accurate scientific assessment in a manner that is compliant with my ethos of science verified by scientists and observed by the public, nothing hidden, nothing obscured, no trade secrets, no concealing statistics by hiding behind certainties.
The Gates Foundation could provide the initial funding, for all I care. And as a long time Slashdotter, I don't say that lightly.
So who's game? Reply with who you sent the grant/funding request to and how I can check the progress. Anyone?