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Submission + - Alzheimer's Disease linked to Sleep Deprivation (newscientist.com) 3

sonnejw0 writes: "NewScientist is reporting a link between sleep deprivation and increased amyloid-beta plaque load, the protein thought responsible for a large part of the symptoms of Alzheimer's Disease, in mice. Medication to abrogate insomnia reduced the plaque load. Also discussed is a recently discovered sleep cycle of amyloid-beta deposition in the brain, in which levels decrease while asleep. From the article:

"Holtzman also tried sending the mice to sleep with a drug that is being trialled for insomnia, called Almorexant. This reduced the amount of plaque-forming protein. He suggests that sleeping for longer could limit the formation of plaques, and perhaps block it altogether."


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