If your startup can't gain enough traction with a couple of 100k it was never going to happen for you you anyway.
Depends on the business you are in. If you are a mobile game startup, then 100k might be enough to see if the idea has legs. If you are an enterprise software platform startup, you need $50m to be competitive and even then you need better tech than your competitors with much deeper pockets. If you are starting a bank, even $50m might not be enough. If you are starting a restaurant, $500k or $1m might be a good amount to start with depending on your location and type of restaurant. But $100k is rarely enough to start more than a small 1 person shop which needs to be in a smallish niche to be successful.