There's already plenty of hostility towards business in the US whether there is reason for it or not.
Their adversarial attitude they regained in the 1980s, with respect to the workforce and other non-business entities, is the source of such hostility.
And how does one kill a business when the business has no presence in the countries where one wants to do the killing.
The US has more than a few allies that are happy to help. Case in point, Huawei - a CPC-run "company" built from stolen parts of Canada's Nortel - has a restricted presence in the US and Australia for matters of national security.