We'll never run out on any timescale that matters, the loss to outer space is only concern over geological time spans.
NOTHING is a concern over geological time periods! The Sun will eventually swallow the Earth- but nobody seems to care too much. Helium depletion on Earth will be a blip on a geological time scale, but during that blip helium will be just a memory to several thousand generations.
Helium is for sissies anyway. I don't care if Donald Trump commutes to work in a blimp refilled with freshly scented helium-3 every morning. MY airship has a pedal-powered generator to pump current through a electrolysis chamber. Hydrogen works so much better than helium anyway... it really gets you high.