I'm about to reboot my computer before I leave town for a couple weeks.
System Up Time: 88 Days, 10 Hours, 26 Minutes, 46 Seconds
I'm running Windows Server 2003 as my desktop OS. I can tell there is plenty of leaked memory I need to free. But I think it has lasted this long because I only run certain applications these days: Firefox, VLC, foobar2000, X-Chat, Azureus, etc.
I've been meaning to switch to Linux for a couple years. Converting the filesystem of my terabyte+ of hard drives is the main holding me back, I think. I don't really play games anymore, though it is nice to have the option.