Forgot your password?

typodupeerror

Comment: Re:A word of caution (Score 1) 117

by pesho (#39067921) Attached to: Yet Another European Government Drops ACTA

You don't appreciate the cultural undertones of what is being said. I assume you will also like the following quote from the same government official in regard to ACTA: "We should never put copy rights ahead of human rights".

Now let me translate these statements for you: "Gee, we did not realize that we can ask for bigger bribes. Now go back and stuff a little more cash into that envelope."

What happened is that being completely clueless about the dynamics of the issue, the government assumed this something that nobody cares about and going along with the flow will procure them some minor favors with the EU bureaucracies and the Bulgarian equivalents of RIAA. Because of the protests, they realized that this is actually a controversial issue, which provides them with a strong bargaining position as far as 'lobbyist' money are concerned.

Comment: It is not about commerce and stem cells (Score 3, Interesting) 332

by pesho (#38909755) Attached to: FDA Regulating Your Stem Cells As Interstate Commerce

This is a moronic summary of a stupid article. This is not about FDA regulating your stem cells, it is about FDA regulating snake oil salesmen, before somebody gets hurt.

Some schmuck finds a loophole in the law that allows him to perform for profit untested medical procedures with questionable (to put it mildly) outcome. FDA has two options:

1. Ignore him and when somebody gets hurt get dragged to congress as a showpiece of a useless government bureaucracy.

2. Cover their bases and use all (no mater how questionable) authority that it can muster to try to shut him down.

Option one is a loosing proposition. Option two is a win-win no-matter how the court decides. If the court allows this to fly (unlikely) they win. If the court laughs at their arguments (more likely) they have covered their asses big time. Now they can turn to congress and say 'We have done what we can, it is your turn now to decide if this should be regulated'. In addition, at any point in the future when a similar situation pops up they are absolved from responsibility.

Comment: Re:So (Score 5, Interesting) 288

by pesho (#38718954) Attached to: BASF Moves GM Plant Research From Europe To US
The GM labeling is a little fuzzy according to this site http://www.innvista.com/health/foods/organics/labeling.htm:

In 1992, the FDA declared that biotech foods were the same as conventional foods – because the biotech companies said so. The number 8 was then instituted since the produce industry thought consumers would prefer genetically modified food moreso than conventionally grown food. It did not take long for them to find out differently. Although the number 8 designation can still be found, it is rare. The biotech industry is also fighting any sort of labeling for their inventions – now that they know consumers really do not want them. As it stands now, Hawaiian papaya is about the only food you will find that has the number 8 in front of it.

Comment: Re:BASF still exists? (Score 4, Informative) 288

by pesho (#38718788) Attached to: BASF Moves GM Plant Research From Europe To US
Wow! These were the times, when we cared about chrome dioxide tapes. Then the CDs came bout and everything went downhill. Seriously, this is one of the largest chemical companies in the world. you don't here about them, because they no longer market to consumers, at least in the US. But if you need 100 metric tons of a pigment, or a polymer, or any other chemical they are the guys to go to.

Comment: Re:Hands of ordinary doctors (Score 1) 136

by pesho (#38699424) Attached to: A DNA Sequencer Cheap Enough For (Some) Doctors' Offices

I feel like I'm watching a bunch of guys on horses making fun of the first automobiles. We're seeing the beginnings of the biggest revolution in medicine since antibiotics. This is going to be huge.

Sure, if you already know what you're sick with then a specific test for that condition will, in certain cases, be cheaper. But the point is you don't know.

You walk into the doctor's office with symptoms that could be cold, flu, the onset of bacterial pneumonia, etc. - and, in a few years, high throughput sequencing will tell you exactly which antibiotics/anitvirals (if any) to take.

Your car analogy is not very appropriate. To begin with I have been riding the automobile in question for couple of years, and its predecessors (microarrays) for about 10 years. You are completely missing the point that the problem here is not the amount of information that a doctor can potentially get from the full genome sequencing. The problem is that at the current state of the art we are unable to digest this information to a point where a doctor can act on it. The reason is that once you go beyond the simple Mendelian genetics, the interactions between different factors become exceedingly complex. You need to take into account multistate interactions of the genome sequence with epigenetic and environmental factors. In addition, having the genomic sequence will not solve your problem of not knowing what to look for. It will tell you even less about what kind of infection you have. In this case we don't really need to use the latest gadget to replace cheap, fast and reliable immunology tests? Kind of reminds me about the machine that says 'BING'.

As it stands now, doctors have more information that they can process. So if your are looking for a revolution that is just starting look at technologies for integrating large amounts of 'fuzzy' information from patient records, medical textbooks and literature, and various medical test to produce accurate diagnosis. Technologies like IBMs Watson and the NIH sponsored i2b2 is the next big thing in medical care.

You have a kid and when he's a few years old it becomes clear that he's got mild mental retardation. You want to know whether the obstetrician messed up during the birth, or your spouse dropped him on his head when you weren't around, or whether he got into the cleaning chemicals under the sink, or whether he got meningitis - or what. Well, if it's genetic, in a few years high throughput sequencing will be able to give you an answer.

You can get the answer if it is genetic now. So going back to the original comment: What are you and your doctor are going to do about it??

Comment: Re:Hands of ordinary doctors (Score 3, Insightful) 136

by pesho (#38695802) Attached to: A DNA Sequencer Cheap Enough For (Some) Doctors' Offices

Yes, you bring your doctor a thumb drive with 3 billion base pairs of your genome, coding for 23,000 genes. Do you know what he says?

"What am I supposed to do with that?"

You hit the nail on the head. There is very little if any useful information for a doctor in full genome sequence, and most of it can be obtained with much cheaper genetic tests. ABI is ramping up the hype because they really need this instrument to be a good seller. Their first bet in the field was on a sequencing by ligation machine (SOLID) which did not sell very well.

Comment: Re:Old test with new buzzword (Score 1) 51

by pesho (#38668250) Attached to: Nanosensors Could Help Reduce Laboratory Animal Testing
Correction: It is not cheaper that current tech and will not increase assay density or performance. The only advantage over most current tests is that it can be used for continuous monitoring of ATP levels in living cells, but I can't find anything that substantiates their claim that it is not toxic. So nothing new here, move along.

QOTD: I've heard about civil Engineers, but I've never met one.

Working...