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Comment: Re:Don't believe the hype (Score 2) 136

by lbbros (#38696056) Attached to: A DNA Sequencer Cheap Enough For (Some) Doctors' Offices

There's another problem to bear in mind: coverage. What is coverage exactly? In terms of "next generation sequencing" (to which this machine belongs to) is how well a part of the genome is covered (sequenced), and that in turns means that the number of fragments (100-150 in the case of Ion Torrent) read for a specific region must be high as possible (those are called "reads").

A good coverage allows you ensure that what you're seeing is real and not some sequencing errors (all technologies suffer from certain types of errors). In the case of Ion Torrent, you usually sequence fragments up to 1 Gbp of sequenced material (G base pairs of DNA), which isn't enough to cover the inter-genic regions or other structural DNA. So usually you do a "reduction step" by either only selecting a handful of genes to be sequenced (mutation screening for example) or by sequencing only the "exome" (exons are the parts of DNA that are actually transcribed to mRNA, the exome is a collective term for all the exons in the genome). That may be useful per se but it's nowhere near a complete genetic map for one individual.

Equipment to do that is much more expensive (500K USD, not counting reagents and other machines).

Comment: Re:No it didnt (Score 1) 234

by lbbros (#37536420) Attached to: Square Enix Admits <em>Final Fantasy XIV</em> Damaged Brand

not be capable of doing worse than FFXI again.

At least from a commercial perspective, XI is not bad at all, being still in operation and (partially) developed. Having played it for about 7 years, I would add that it was not that bad despite clearly a very unrewarding set up. In particular, the main scenario (and even more in particular the Chains of Promathia expansion) are well worth the FF name.

Comment: Re:the only thing worse (Score 1) 150

by lbbros (#35705678) Attached to: China Detects 10 Cases of Radiation Contamination, 2 In Hospital

at least the hysterical can plead ignorance. what's your excuse asshole?

That physics does not follow hysteria. The situation is serious, but the media are blowing it way out of proportion.

And as someone said, detectable means nothing. The detection systems are so precise they can identify the natural background.

Whenever I feel like exercise, I lie down until the feeling passes.

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