Comment: Spice bred a large family tree (Score 2) 314
There were two very different versions of SPICE - SPICE2 was a fortran program, and is the basis for the PC version PSPICE (Microsim>OrCAD>Cadence) and minicomputer version HSPICE, though many newer simulators are based on the code for spice3 re-written by a subsequent Berkeley effort in c. Its legacy in electronics engineering is such that even independently generated simulators (Eldo, spectre) rely on the conventions and methods from SPICE, though incorporating incremental improvements (a new algorithm here or there, and distinguishable mainly by how it differs from SPICE).